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Generation of Integration‐Free Induced Pluripotent Stem Cells from Urine‐Derived Cells Isolated from Individuals with Down Syndrome

Down syndrome (DS) is a genetic disorder caused by trisomy 21 (T21). Over the past two decades, the use of mouse models has led to significant advances in the understanding of mechanisms underlying various phenotypic features and comorbidities secondary to T21 and even informed the design of clinica...

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Detalles Bibliográficos
Autores principales:	M. Lee, Young, Zampieri, Bruna L., Scott‐McKean, Jonah J., Johnson, Mark W., Costa, Alberto C.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Translational Research Articles and Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689751/ https://www.ncbi.nlm.nih.gov/pubmed/28371411 http://dx.doi.org/10.1002/sctm.16-0128

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