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Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles
Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell‐related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Ve...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689784/ https://www.ncbi.nlm.nih.gov/pubmed/28714557 http://dx.doi.org/10.1002/sctm.17-0055 |
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| author | Reiner, Agnes T. Witwer, Kenneth W. van Balkom, Bas W.M. de Beer, Joel Brodie, Chaya Corteling, Randolph L. Gabrielsson, Susanne Gimona, Mario Ibrahim, Ahmed G. de Kleijn, Dominique Lai, Charles P. Lötvall, Jan del Portillo, Hernando A. Reischl, Ilona G. Riazifar, Milad Salomon, Carlos Tahara, Hidetoshi Toh, Wei Seong Wauben, Marca H.M. Yang, Vicky K. Yang, Yijun Yeo, Ronne Wee Yeh Yin, Hang Giebel, Bernd Rohde, Eva Lim, Sai Kiang |
| author_facet | Reiner, Agnes T. Witwer, Kenneth W. van Balkom, Bas W.M. de Beer, Joel Brodie, Chaya Corteling, Randolph L. Gabrielsson, Susanne Gimona, Mario Ibrahim, Ahmed G. de Kleijn, Dominique Lai, Charles P. Lötvall, Jan del Portillo, Hernando A. Reischl, Ilona G. Riazifar, Milad Salomon, Carlos Tahara, Hidetoshi Toh, Wei Seong Wauben, Marca H.M. Yang, Vicky K. Yang, Yijun Yeo, Ronne Wee Yeh Yin, Hang Giebel, Bernd Rohde, Eva Lim, Sai Kiang |
| author_sort | Reiner, Agnes T. |
| collection | PubMed |
| description | Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell‐related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV‐based therapeutics at the preclinical and clinical levels. This review outlines topic‐specific action items that, if addressed, will enhance the development of best‐practice models for EV therapies. Stem Cells Translational Medicine 2017;6:1730–1739 |
| format | Online Article Text |
| id | pubmed-5689784 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-56897842017-11-24 Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles Reiner, Agnes T. Witwer, Kenneth W. van Balkom, Bas W.M. de Beer, Joel Brodie, Chaya Corteling, Randolph L. Gabrielsson, Susanne Gimona, Mario Ibrahim, Ahmed G. de Kleijn, Dominique Lai, Charles P. Lötvall, Jan del Portillo, Hernando A. Reischl, Ilona G. Riazifar, Milad Salomon, Carlos Tahara, Hidetoshi Toh, Wei Seong Wauben, Marca H.M. Yang, Vicky K. Yang, Yijun Yeo, Ronne Wee Yeh Yin, Hang Giebel, Bernd Rohde, Eva Lim, Sai Kiang Stem Cells Transl Med Translational Research Articles and Reviews Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell‐related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV‐based therapeutics at the preclinical and clinical levels. This review outlines topic‐specific action items that, if addressed, will enhance the development of best‐practice models for EV therapies. Stem Cells Translational Medicine 2017;6:1730–1739 John Wiley and Sons Inc. 2017-07-17 /pmc/articles/PMC5689784/ /pubmed/28714557 http://dx.doi.org/10.1002/sctm.17-0055 Text en © 2017 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Translational Research Articles and Reviews Reiner, Agnes T. Witwer, Kenneth W. van Balkom, Bas W.M. de Beer, Joel Brodie, Chaya Corteling, Randolph L. Gabrielsson, Susanne Gimona, Mario Ibrahim, Ahmed G. de Kleijn, Dominique Lai, Charles P. Lötvall, Jan del Portillo, Hernando A. Reischl, Ilona G. Riazifar, Milad Salomon, Carlos Tahara, Hidetoshi Toh, Wei Seong Wauben, Marca H.M. Yang, Vicky K. Yang, Yijun Yeo, Ronne Wee Yeh Yin, Hang Giebel, Bernd Rohde, Eva Lim, Sai Kiang Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles |
| title | Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles |
| title_full | Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles |
| title_fullStr | Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles |
| title_full_unstemmed | Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles |
| title_short | Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles |
| title_sort | concise review: developing best‐practice models for the therapeutic use of extracellular vesicles |
| topic | Translational Research Articles and Reviews |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689784/ https://www.ncbi.nlm.nih.gov/pubmed/28714557 http://dx.doi.org/10.1002/sctm.17-0055 |
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