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MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities

Junctions of fields are known to be susceptible to developing cold or hot spots in the presence of even small geometrical misalignments. Reduction of these dose inhomogeneities can be accomplished through decreasing the dose gradients in the penumbra, but currently it cannot be done for enhanced dyn...

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Autores principales: Szpala, Stanislaw, Kohli, Kirpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689845/
https://www.ncbi.nlm.nih.gov/pubmed/28422401
http://dx.doi.org/10.1002/acm2.12082
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author Szpala, Stanislaw
Kohli, Kirpal
author_facet Szpala, Stanislaw
Kohli, Kirpal
author_sort Szpala, Stanislaw
collection PubMed
description Junctions of fields are known to be susceptible to developing cold or hot spots in the presence of even small geometrical misalignments. Reduction of these dose inhomogeneities can be accomplished through decreasing the dose gradients in the penumbra, but currently it cannot be done for enhanced dynamic wedges (EDW). An MLC‐based penumbra softener was developed in the developer mode of TrueBeam linacs to reduce dose gradients across the side border of EDWs. The movement of each leaf was individually synchronized with the movement of the dynamic Y jaw to soften the penumbra in the same manner along the entire field border, in spite of the presence of the dose gradient of the EDW. Junction homogeneity upon field misalignment for side‐matched EDWs was examined with the MV imager. The fluence inhomogeneities were reduced from about 30% per mm of shift of the field borders for the conventional EDW to about 2% per mm for the softened‐penumbra plan. The junction in a four‐field monoisocentric breast plan delivered to the Rando phantom was assessed with film. The dose inhomogeneities across the junction in the superior‐inferior direction were reduced from about 20% to 25% per mm for the conventional fields to about 5% per mm. The dose near the softened junction of the breast plan with no shifts did not deviate from the conventional plan by more than about 4%. The newly‐developed softened‐penumbra junction of EDW (and/or open) fields was shown to reduce sensitivity to misalignments without increasing complexity of the planning or delivery. This methodology needs to be adopted by the manufacturers for clinical use.
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spelling pubmed-56898452018-04-02 MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities Szpala, Stanislaw Kohli, Kirpal J Appl Clin Med Phys Radiation Oncology Physics Junctions of fields are known to be susceptible to developing cold or hot spots in the presence of even small geometrical misalignments. Reduction of these dose inhomogeneities can be accomplished through decreasing the dose gradients in the penumbra, but currently it cannot be done for enhanced dynamic wedges (EDW). An MLC‐based penumbra softener was developed in the developer mode of TrueBeam linacs to reduce dose gradients across the side border of EDWs. The movement of each leaf was individually synchronized with the movement of the dynamic Y jaw to soften the penumbra in the same manner along the entire field border, in spite of the presence of the dose gradient of the EDW. Junction homogeneity upon field misalignment for side‐matched EDWs was examined with the MV imager. The fluence inhomogeneities were reduced from about 30% per mm of shift of the field borders for the conventional EDW to about 2% per mm for the softened‐penumbra plan. The junction in a four‐field monoisocentric breast plan delivered to the Rando phantom was assessed with film. The dose inhomogeneities across the junction in the superior‐inferior direction were reduced from about 20% to 25% per mm for the conventional fields to about 5% per mm. The dose near the softened junction of the breast plan with no shifts did not deviate from the conventional plan by more than about 4%. The newly‐developed softened‐penumbra junction of EDW (and/or open) fields was shown to reduce sensitivity to misalignments without increasing complexity of the planning or delivery. This methodology needs to be adopted by the manufacturers for clinical use. John Wiley and Sons Inc. 2017-04-19 /pmc/articles/PMC5689845/ /pubmed/28422401 http://dx.doi.org/10.1002/acm2.12082 Text en © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Szpala, Stanislaw
Kohli, Kirpal
MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities
title MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities
title_full MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities
title_fullStr MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities
title_full_unstemmed MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities
title_short MLC‐based penumbra softener of EDW borders to reduce junction inhomogeneities
title_sort mlc‐based penumbra softener of edw borders to reduce junction inhomogeneities
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689845/
https://www.ncbi.nlm.nih.gov/pubmed/28422401
http://dx.doi.org/10.1002/acm2.12082
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