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Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator

Model‐based dose calculation algorithms have recently been incorporated into brachytherapy treatment planning systems, and their introduction requires critical evaluation before clinical implementation. Here, we present an experimental evaluation of Oncentra(®) Brachy Advanced Collapsed‐cone Engine...

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Autores principales: Cawston‐Grant, Brie, Morrison, Hali, Menon, Geetha, Sloboda, Ron S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689852/
https://www.ncbi.nlm.nih.gov/pubmed/28317325
http://dx.doi.org/10.1002/acm2.12061
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author Cawston‐Grant, Brie
Morrison, Hali
Menon, Geetha
Sloboda, Ron S
author_facet Cawston‐Grant, Brie
Morrison, Hali
Menon, Geetha
Sloboda, Ron S
author_sort Cawston‐Grant, Brie
collection PubMed
description Model‐based dose calculation algorithms have recently been incorporated into brachytherapy treatment planning systems, and their introduction requires critical evaluation before clinical implementation. Here, we present an experimental evaluation of Oncentra(®) Brachy Advanced Collapsed‐cone Engine (ACE) for a multichannel vaginal cylinder (MCVC) applicator using radiochromic film. A uniform dose of 500 cGy was specified to the surface of the MCVC using the TG‐43 dose formalism under two conditions: (a) with only the central channel loaded or (b) only the peripheral channels loaded. Film measurements were made at the applicator surface and compared to the doses calculated using TG‐43, standard accuracy ACE (sACE), and high accuracy ACE (hACE). When the central channel of the applicator was used, the film measurements showed a dose increase of (11 ± 8)% (k = 2) above the two outer grooves on the applicator surface. This increase in dose was confirmed with the hACE calculations, but was not confirmed with the sACE calculations at the applicator surface. When the peripheral channels were used, a periodic azimuthal variation in measured dose was observed around the applicator. The sACE and hACE calculations confirmed this variation and agreed within 1% of each other at the applicator surface. Additionally for the film measurements with the central channel used, a baseline dose variation of (10 ± 4)% (k = 2) of the mean dose was observed azimuthally around the applicator surface, which can be explained by offset source positioning in the central channel.
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spelling pubmed-56898522018-04-02 Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator Cawston‐Grant, Brie Morrison, Hali Menon, Geetha Sloboda, Ron S J Appl Clin Med Phys Radiation Oncology Physics Model‐based dose calculation algorithms have recently been incorporated into brachytherapy treatment planning systems, and their introduction requires critical evaluation before clinical implementation. Here, we present an experimental evaluation of Oncentra(®) Brachy Advanced Collapsed‐cone Engine (ACE) for a multichannel vaginal cylinder (MCVC) applicator using radiochromic film. A uniform dose of 500 cGy was specified to the surface of the MCVC using the TG‐43 dose formalism under two conditions: (a) with only the central channel loaded or (b) only the peripheral channels loaded. Film measurements were made at the applicator surface and compared to the doses calculated using TG‐43, standard accuracy ACE (sACE), and high accuracy ACE (hACE). When the central channel of the applicator was used, the film measurements showed a dose increase of (11 ± 8)% (k = 2) above the two outer grooves on the applicator surface. This increase in dose was confirmed with the hACE calculations, but was not confirmed with the sACE calculations at the applicator surface. When the peripheral channels were used, a periodic azimuthal variation in measured dose was observed around the applicator. The sACE and hACE calculations confirmed this variation and agreed within 1% of each other at the applicator surface. Additionally for the film measurements with the central channel used, a baseline dose variation of (10 ± 4)% (k = 2) of the mean dose was observed azimuthally around the applicator surface, which can be explained by offset source positioning in the central channel. John Wiley and Sons Inc. 2017-03-20 /pmc/articles/PMC5689852/ /pubmed/28317325 http://dx.doi.org/10.1002/acm2.12061 Text en © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Cawston‐Grant, Brie
Morrison, Hali
Menon, Geetha
Sloboda, Ron S
Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator
title Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator
title_full Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator
title_fullStr Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator
title_full_unstemmed Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator
title_short Experimental verification of Advanced Collapsed‐cone Engine for use with a multichannel vaginal cylinder applicator
title_sort experimental verification of advanced collapsed‐cone engine for use with a multichannel vaginal cylinder applicator
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689852/
https://www.ncbi.nlm.nih.gov/pubmed/28317325
http://dx.doi.org/10.1002/acm2.12061
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