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Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation

Monte Carlo (MC) simulation has been used to generate commissioning data for the beam modeling of treatment planning system (TPS). We have developed a method called radial projection (RP) for postprocessing of MC‐simulation‐generated data. We used the RP method to reduce the statistical uncertainty...

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Autores principales: Ding, Xiaoning, Liu, Wei, Shen, Jiajian, Anand, Aman, Stoker, Joshua B., Hu, Yanle, Bues, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689928/
https://www.ncbi.nlm.nih.gov/pubmed/28921881
http://dx.doi.org/10.1002/acm2.12184
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author Ding, Xiaoning
Liu, Wei
Shen, Jiajian
Anand, Aman
Stoker, Joshua B.
Hu, Yanle
Bues, Martin
author_facet Ding, Xiaoning
Liu, Wei
Shen, Jiajian
Anand, Aman
Stoker, Joshua B.
Hu, Yanle
Bues, Martin
author_sort Ding, Xiaoning
collection PubMed
description Monte Carlo (MC) simulation has been used to generate commissioning data for the beam modeling of treatment planning system (TPS). We have developed a method called radial projection (RP) for postprocessing of MC‐simulation‐generated data. We used the RP method to reduce the statistical uncertainty of the lateral profile of proton pencil beams with axial symmetry. The RP method takes advantage of the axial symmetry of dose distribution to use the mean value of multiple independent scores as the representative score. Using the mean as the representative value rather than any individual score results in substantial reduction in statistical uncertainty. Herein, we present the concept and step‐by‐step implementation of the RP method, as well as show the advantage of the RP method over conventional measurement methods for generating lateral profile. Lateral profiles generated by both methods were compared to demonstrate the uncertainty reduction qualitatively, and standard error comparison was performed to demonstrate the reduction quantitatively. The comparisons showed that statistical uncertainty was reduced substantially by the RP method. Using the RP method to postprocess MC data, the corresponding MC simulation time was reduced by a factor of 10 without quality reduction in the generated result from the MC data. We concluded that the RP method is an effective technique to increase MC simulation efficiency for generating lateral profiles for axially symmetric pencil beams.
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spelling pubmed-56899282018-04-02 Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation Ding, Xiaoning Liu, Wei Shen, Jiajian Anand, Aman Stoker, Joshua B. Hu, Yanle Bues, Martin J Appl Clin Med Phys Radiation Oncology Physics Monte Carlo (MC) simulation has been used to generate commissioning data for the beam modeling of treatment planning system (TPS). We have developed a method called radial projection (RP) for postprocessing of MC‐simulation‐generated data. We used the RP method to reduce the statistical uncertainty of the lateral profile of proton pencil beams with axial symmetry. The RP method takes advantage of the axial symmetry of dose distribution to use the mean value of multiple independent scores as the representative score. Using the mean as the representative value rather than any individual score results in substantial reduction in statistical uncertainty. Herein, we present the concept and step‐by‐step implementation of the RP method, as well as show the advantage of the RP method over conventional measurement methods for generating lateral profile. Lateral profiles generated by both methods were compared to demonstrate the uncertainty reduction qualitatively, and standard error comparison was performed to demonstrate the reduction quantitatively. The comparisons showed that statistical uncertainty was reduced substantially by the RP method. Using the RP method to postprocess MC data, the corresponding MC simulation time was reduced by a factor of 10 without quality reduction in the generated result from the MC data. We concluded that the RP method is an effective technique to increase MC simulation efficiency for generating lateral profiles for axially symmetric pencil beams. John Wiley and Sons Inc. 2017-09-18 /pmc/articles/PMC5689928/ /pubmed/28921881 http://dx.doi.org/10.1002/acm2.12184 Text en © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ding, Xiaoning
Liu, Wei
Shen, Jiajian
Anand, Aman
Stoker, Joshua B.
Hu, Yanle
Bues, Martin
Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation
title Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation
title_full Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation
title_fullStr Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation
title_full_unstemmed Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation
title_short Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation
title_sort use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by monte carlo simulation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689928/
https://www.ncbi.nlm.nih.gov/pubmed/28921881
http://dx.doi.org/10.1002/acm2.12184
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