Cargando…
Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy
Deep inspiration breath‐hold (DIBH) radiotherapy for left‐sided breast cancer can reduce cardiac exposure and internal motion. We modified our in‐house treatment planning system (TPS) to retrospectively analyze breath‐hold motion log files to calculate the dosimetric effect of the motion during brea...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690002/ https://www.ncbi.nlm.nih.gov/pubmed/26219001 http://dx.doi.org/10.1120/jacmp.v16i4.5358 |
_version_ | 1783279506831704064 |
---|---|
author | Tang, Xiaoli Cullip, Tim Dooley, John Zagar, Timothy Jones, Ellen Chang, Sha Zhu, Xiaofeng Lian, Jun Marks, Lawrence |
author_facet | Tang, Xiaoli Cullip, Tim Dooley, John Zagar, Timothy Jones, Ellen Chang, Sha Zhu, Xiaofeng Lian, Jun Marks, Lawrence |
author_sort | Tang, Xiaoli |
collection | PubMed |
description | Deep inspiration breath‐hold (DIBH) radiotherapy for left‐sided breast cancer can reduce cardiac exposure and internal motion. We modified our in‐house treatment planning system (TPS) to retrospectively analyze breath‐hold motion log files to calculate the dosimetric effect of the motion during breath hold. Thirty left‐sided supine DIBH breast patients treated using AlignRT were studied. Breath‐hold motion was recorded — three translational and three rotational displacements of the treatment surface — the Real Time Deltas (RTD). The corresponding delivered dose was estimated using the beam‐on portions of the RTDs. Each motion was used to calculate dose, and the final estimated dose was the equally weighted average of the multiple resultant doses. Ten of thirty patients had internal mammary nodes (IMN) purposefully included in the tangential fields, and we evaluated the percentage of IMN covered by 40 Gy. The planned and delivered heart mean dose, lungs V20 (volume of the lungs receiving [Formula: see text]), percentage of IMN covered by 40 Gy, and IMN mean dose were compared. The averaged mean and standard deviation of the beam‐on portions of the absolute RTDs were [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , and [Formula: see text] , for vertical, longitudinal, lateral, yaw, roll, and pitch, respectively. The averaged planned and delivered mean heart dose were 99 and 101 cGy. Lungs V20 were 6.59% and 6.74%. IMN 40 Gy coverage was 83% and 77%, and mean IMN dose was 4642 and 4518 cGy. The averaged mean motion during DIBH was smaller than 1 mm and 1°, which reflects the relative reproducibility of the patient breath hold. On average, the mean heart dose and lungs V20 were reasonably close to what have been planned. IMN 40 Gy coverage might be modestly reduced for certain cases. PACS number: 87.55.km, 87.55.N |
format | Online Article Text |
id | pubmed-5690002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56900022018-04-02 Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy Tang, Xiaoli Cullip, Tim Dooley, John Zagar, Timothy Jones, Ellen Chang, Sha Zhu, Xiaofeng Lian, Jun Marks, Lawrence J Appl Clin Med Phys Radiation Oncology Physics Deep inspiration breath‐hold (DIBH) radiotherapy for left‐sided breast cancer can reduce cardiac exposure and internal motion. We modified our in‐house treatment planning system (TPS) to retrospectively analyze breath‐hold motion log files to calculate the dosimetric effect of the motion during breath hold. Thirty left‐sided supine DIBH breast patients treated using AlignRT were studied. Breath‐hold motion was recorded — three translational and three rotational displacements of the treatment surface — the Real Time Deltas (RTD). The corresponding delivered dose was estimated using the beam‐on portions of the RTDs. Each motion was used to calculate dose, and the final estimated dose was the equally weighted average of the multiple resultant doses. Ten of thirty patients had internal mammary nodes (IMN) purposefully included in the tangential fields, and we evaluated the percentage of IMN covered by 40 Gy. The planned and delivered heart mean dose, lungs V20 (volume of the lungs receiving [Formula: see text]), percentage of IMN covered by 40 Gy, and IMN mean dose were compared. The averaged mean and standard deviation of the beam‐on portions of the absolute RTDs were [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , and [Formula: see text] , for vertical, longitudinal, lateral, yaw, roll, and pitch, respectively. The averaged planned and delivered mean heart dose were 99 and 101 cGy. Lungs V20 were 6.59% and 6.74%. IMN 40 Gy coverage was 83% and 77%, and mean IMN dose was 4642 and 4518 cGy. The averaged mean motion during DIBH was smaller than 1 mm and 1°, which reflects the relative reproducibility of the patient breath hold. On average, the mean heart dose and lungs V20 were reasonably close to what have been planned. IMN 40 Gy coverage might be modestly reduced for certain cases. PACS number: 87.55.km, 87.55.N John Wiley and Sons Inc. 2015-07-08 /pmc/articles/PMC5690002/ /pubmed/26219001 http://dx.doi.org/10.1120/jacmp.v16i4.5358 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Tang, Xiaoli Cullip, Tim Dooley, John Zagar, Timothy Jones, Ellen Chang, Sha Zhu, Xiaofeng Lian, Jun Marks, Lawrence Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
title | Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
title_full | Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
title_fullStr | Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
title_full_unstemmed | Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
title_short | Dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
title_sort | dosimetric effect due to the motion during deep inspiration breath hold for left‐sided breast cancer radiotherapy |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690002/ https://www.ncbi.nlm.nih.gov/pubmed/26219001 http://dx.doi.org/10.1120/jacmp.v16i4.5358 |
work_keys_str_mv | AT tangxiaoli dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT culliptim dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT dooleyjohn dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT zagartimothy dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT jonesellen dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT changsha dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT zhuxiaofeng dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT lianjun dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy AT markslawrence dosimetriceffectduetothemotionduringdeepinspirationbreathholdforleftsidedbreastcancerradiotherapy |