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Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery
The purpose of this study is to characterize the dosimetric properties and accuracy of a novel treatment platform (Edge radiosurgery system) for localizing and treating patients with frameless, image‐guided stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Initial measuremen...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690003/ https://www.ncbi.nlm.nih.gov/pubmed/26218998 http://dx.doi.org/10.1120/jacmp.v16i4.5313 |
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author | Wen, Ning Li, Haisen Song, Kwang Chin‐Snyder, Karen Qin, Yujiao Kim, Jinkoo Bellon, Maria Gulam, Misbah Gardner, Stephen Doemer, Anthony Devpura, Suneetha Gordon, James Chetty, Indrin Siddiqui, Farzan Ajlouni, Munther Pompa, Robert Hammoud, Zane Simoff, Michael Kalkanis, Steven Movsas, Benjamin Siddiqui, M. Salim |
author_facet | Wen, Ning Li, Haisen Song, Kwang Chin‐Snyder, Karen Qin, Yujiao Kim, Jinkoo Bellon, Maria Gulam, Misbah Gardner, Stephen Doemer, Anthony Devpura, Suneetha Gordon, James Chetty, Indrin Siddiqui, Farzan Ajlouni, Munther Pompa, Robert Hammoud, Zane Simoff, Michael Kalkanis, Steven Movsas, Benjamin Siddiqui, M. Salim |
author_sort | Wen, Ning |
collection | PubMed |
description | The purpose of this study is to characterize the dosimetric properties and accuracy of a novel treatment platform (Edge radiosurgery system) for localizing and treating patients with frameless, image‐guided stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Initial measurements of various components of the system, such as a comprehensive assessment of the dosimetric properties of the flattening filter‐free (FFF) beams for both high definition (HD120) MLC and conical cone‐based treatment, positioning accuracy and beam attenuation of a six degree of freedom (6DoF) couch, treatment head leakage test, and integrated end‐to‐end accuracy tests, have been performed. The end‐to‐end test of the system was performed by CT imaging a phantom and registering hidden targets on the treatment couch to determine the localization accuracy of the optical surface monitoring system (OSMS), cone‐beam CT (CBCT), and MV imaging systems, as well as the radiation isocenter targeting accuracy. The deviations between the percent depth‐dose curves acquired on the new linac‐based system (Edge), and the previously published machine with FFF beams (TrueBeam) beyond [Formula: see text] were within 1.0% for both energies. The maximum deviation of output factors between the Edge and TrueBeam was 1.6%. The optimized dosimetric leaf gap values, which were fitted using Eclipse dose calculations and measurements based on representative spine radiosurgery plans, were 0.700 mm and 1.000 mm, respectively. For the conical cones, 6X FFF has sharper penumbra ranging from [Formula: see text] (80%‐20%) and [Formula: see text] (90%‐10%) relative to 10X FFF, which has [Formula: see text] and [Formula: see text] , respectively. The relative attenuation measurements of the couch for PA, PA (rails‐in), oblique, oblique (rails‐out), oblique (rails‐in) were: [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] for 6X FFF and [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] for 10X FFF, respectively, with a slight decrease in attenuation versus field size. The systematic deviation between the OSMS and CBCT was [Formula: see text] , [Formula: see text] , and [Formula: see text] in the vertical, longitudinal, and lateral directions. The mean values and standard deviations of the average deviation and maximum deviation of the daily Winston‐Lutz tests over three months are [Formula: see text] and [Formula: see text] , respectively. Initial testing of this novel system demonstrates the technology to be highly accurate and suitable for frameless, linac‐based SRS and SBRT treatment. PACS number: 87.56.J‐ |
format | Online Article Text |
id | pubmed-5690003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56900032018-04-02 Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery Wen, Ning Li, Haisen Song, Kwang Chin‐Snyder, Karen Qin, Yujiao Kim, Jinkoo Bellon, Maria Gulam, Misbah Gardner, Stephen Doemer, Anthony Devpura, Suneetha Gordon, James Chetty, Indrin Siddiqui, Farzan Ajlouni, Munther Pompa, Robert Hammoud, Zane Simoff, Michael Kalkanis, Steven Movsas, Benjamin Siddiqui, M. Salim J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study is to characterize the dosimetric properties and accuracy of a novel treatment platform (Edge radiosurgery system) for localizing and treating patients with frameless, image‐guided stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Initial measurements of various components of the system, such as a comprehensive assessment of the dosimetric properties of the flattening filter‐free (FFF) beams for both high definition (HD120) MLC and conical cone‐based treatment, positioning accuracy and beam attenuation of a six degree of freedom (6DoF) couch, treatment head leakage test, and integrated end‐to‐end accuracy tests, have been performed. The end‐to‐end test of the system was performed by CT imaging a phantom and registering hidden targets on the treatment couch to determine the localization accuracy of the optical surface monitoring system (OSMS), cone‐beam CT (CBCT), and MV imaging systems, as well as the radiation isocenter targeting accuracy. The deviations between the percent depth‐dose curves acquired on the new linac‐based system (Edge), and the previously published machine with FFF beams (TrueBeam) beyond [Formula: see text] were within 1.0% for both energies. The maximum deviation of output factors between the Edge and TrueBeam was 1.6%. The optimized dosimetric leaf gap values, which were fitted using Eclipse dose calculations and measurements based on representative spine radiosurgery plans, were 0.700 mm and 1.000 mm, respectively. For the conical cones, 6X FFF has sharper penumbra ranging from [Formula: see text] (80%‐20%) and [Formula: see text] (90%‐10%) relative to 10X FFF, which has [Formula: see text] and [Formula: see text] , respectively. The relative attenuation measurements of the couch for PA, PA (rails‐in), oblique, oblique (rails‐out), oblique (rails‐in) were: [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] for 6X FFF and [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] for 10X FFF, respectively, with a slight decrease in attenuation versus field size. The systematic deviation between the OSMS and CBCT was [Formula: see text] , [Formula: see text] , and [Formula: see text] in the vertical, longitudinal, and lateral directions. The mean values and standard deviations of the average deviation and maximum deviation of the daily Winston‐Lutz tests over three months are [Formula: see text] and [Formula: see text] , respectively. Initial testing of this novel system demonstrates the technology to be highly accurate and suitable for frameless, linac‐based SRS and SBRT treatment. PACS number: 87.56.J‐ John Wiley and Sons Inc. 2015-07-08 /pmc/articles/PMC5690003/ /pubmed/26218998 http://dx.doi.org/10.1120/jacmp.v16i4.5313 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Wen, Ning Li, Haisen Song, Kwang Chin‐Snyder, Karen Qin, Yujiao Kim, Jinkoo Bellon, Maria Gulam, Misbah Gardner, Stephen Doemer, Anthony Devpura, Suneetha Gordon, James Chetty, Indrin Siddiqui, Farzan Ajlouni, Munther Pompa, Robert Hammoud, Zane Simoff, Michael Kalkanis, Steven Movsas, Benjamin Siddiqui, M. Salim Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
title | Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
title_full | Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
title_fullStr | Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
title_full_unstemmed | Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
title_short | Characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
title_sort | characteristics of a novel treatment system for linear accelerator–based stereotactic radiosurgery |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690003/ https://www.ncbi.nlm.nih.gov/pubmed/26218998 http://dx.doi.org/10.1120/jacmp.v16i4.5313 |
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