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Measurement‐guided volumetric dose reconstruction for helical tomotherapy

It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed — on patient or phantom datasets — using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analy...

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Autores principales: Stambaugh, Cassandra, Nelms, Benjamin, Wolf, Theresa, Mueller, Richard, Geurts, Mark, Opp, Daniel, Zhang, Geoffrey, Moros, Eduardo, Feygelman, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690083/
https://www.ncbi.nlm.nih.gov/pubmed/26103199
http://dx.doi.org/10.1120/jacmp.v16i2.5298
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author Stambaugh, Cassandra
Nelms, Benjamin
Wolf, Theresa
Mueller, Richard
Geurts, Mark
Opp, Daniel
Zhang, Geoffrey
Moros, Eduardo
Feygelman, Vladimir
author_facet Stambaugh, Cassandra
Nelms, Benjamin
Wolf, Theresa
Mueller, Richard
Geurts, Mark
Opp, Daniel
Zhang, Geoffrey
Moros, Eduardo
Feygelman, Vladimir
author_sort Stambaugh, Cassandra
collection PubMed
description It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed — on patient or phantom datasets — using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analysis of the agreement between the planned and delivered dose, including direct comparison of the dose‐volume histograms. While conceptually similar to modulated arc techniques, helical tomotherapy introduces significant challenges to the PDP formalism, arising primarily from TomoTherapy delivery dynamics. The temporal characteristics of the delivery are of the same order or shorter than the dosimeter's update interval (50 ms). Additionally, the prevalence of often small and complex segments, particularly with the 1 cm Y jaw setting, lead to challenges related to detector spacing. Here, we present and test a novel method of tomotherapy‐PDP (TPDP) designed to meet these challenges. One of the novel techniques introduced for TPDP is organization of the subbeams into larger subunits called sectors, which assures more robust synchronization of the measurement and delivery dynamics. Another important change is the optional application of a correction based on ion chamber (IC) measurements in the phantom. The TPDP method was validated by direct comparisons to the IC and an independent, biplanar diode array dosimeter previously evaluated for tomotherapy delivery quality assurance. Nineteen plans with varying complexity were analyzed for the 2.5 cm tomotherapy jaw setting and 18 for the 1 cm opening. The dose differences between the TPDP and IC were [Formula: see text] and [Formula: see text] , for 2.5 and 1.0 cm jaw plans, respectively. Gamma analysis agreement rates between TPDP and the independent array were: [Formula: see text] (using 3% global normalization/3 mm criteria) and [Formula: see text] (using 2% global/2 mm) for the 2.5 cm jaw plans; for 1 cm plans, they were [Formula: see text] (3% G/3) and [Formula: see text] (2% G/2). We conclude that TPDP is capable of volumetric dose reconstruction with acceptable accuracy. However, the challenges of fast tomotherapy delivery dynamics make TPDP less precise than the IMRT/VMAT PDP version, particularly for the 1 cm jaw setting. PACS number: 87.55Qr
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spelling pubmed-56900832018-04-02 Measurement‐guided volumetric dose reconstruction for helical tomotherapy Stambaugh, Cassandra Nelms, Benjamin Wolf, Theresa Mueller, Richard Geurts, Mark Opp, Daniel Zhang, Geoffrey Moros, Eduardo Feygelman, Vladimir J Appl Clin Med Phys Radiation Oncology Physics It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed — on patient or phantom datasets — using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analysis of the agreement between the planned and delivered dose, including direct comparison of the dose‐volume histograms. While conceptually similar to modulated arc techniques, helical tomotherapy introduces significant challenges to the PDP formalism, arising primarily from TomoTherapy delivery dynamics. The temporal characteristics of the delivery are of the same order or shorter than the dosimeter's update interval (50 ms). Additionally, the prevalence of often small and complex segments, particularly with the 1 cm Y jaw setting, lead to challenges related to detector spacing. Here, we present and test a novel method of tomotherapy‐PDP (TPDP) designed to meet these challenges. One of the novel techniques introduced for TPDP is organization of the subbeams into larger subunits called sectors, which assures more robust synchronization of the measurement and delivery dynamics. Another important change is the optional application of a correction based on ion chamber (IC) measurements in the phantom. The TPDP method was validated by direct comparisons to the IC and an independent, biplanar diode array dosimeter previously evaluated for tomotherapy delivery quality assurance. Nineteen plans with varying complexity were analyzed for the 2.5 cm tomotherapy jaw setting and 18 for the 1 cm opening. The dose differences between the TPDP and IC were [Formula: see text] and [Formula: see text] , for 2.5 and 1.0 cm jaw plans, respectively. Gamma analysis agreement rates between TPDP and the independent array were: [Formula: see text] (using 3% global normalization/3 mm criteria) and [Formula: see text] (using 2% global/2 mm) for the 2.5 cm jaw plans; for 1 cm plans, they were [Formula: see text] (3% G/3) and [Formula: see text] (2% G/2). We conclude that TPDP is capable of volumetric dose reconstruction with acceptable accuracy. However, the challenges of fast tomotherapy delivery dynamics make TPDP less precise than the IMRT/VMAT PDP version, particularly for the 1 cm jaw setting. PACS number: 87.55Qr John Wiley and Sons Inc. 2015-03-08 /pmc/articles/PMC5690083/ /pubmed/26103199 http://dx.doi.org/10.1120/jacmp.v16i2.5298 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Stambaugh, Cassandra
Nelms, Benjamin
Wolf, Theresa
Mueller, Richard
Geurts, Mark
Opp, Daniel
Zhang, Geoffrey
Moros, Eduardo
Feygelman, Vladimir
Measurement‐guided volumetric dose reconstruction for helical tomotherapy
title Measurement‐guided volumetric dose reconstruction for helical tomotherapy
title_full Measurement‐guided volumetric dose reconstruction for helical tomotherapy
title_fullStr Measurement‐guided volumetric dose reconstruction for helical tomotherapy
title_full_unstemmed Measurement‐guided volumetric dose reconstruction for helical tomotherapy
title_short Measurement‐guided volumetric dose reconstruction for helical tomotherapy
title_sort measurement‐guided volumetric dose reconstruction for helical tomotherapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690083/
https://www.ncbi.nlm.nih.gov/pubmed/26103199
http://dx.doi.org/10.1120/jacmp.v16i2.5298
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