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Measurement‐guided volumetric dose reconstruction for helical tomotherapy
It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed — on patient or phantom datasets — using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analy...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690083/ https://www.ncbi.nlm.nih.gov/pubmed/26103199 http://dx.doi.org/10.1120/jacmp.v16i2.5298 |
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author | Stambaugh, Cassandra Nelms, Benjamin Wolf, Theresa Mueller, Richard Geurts, Mark Opp, Daniel Zhang, Geoffrey Moros, Eduardo Feygelman, Vladimir |
author_facet | Stambaugh, Cassandra Nelms, Benjamin Wolf, Theresa Mueller, Richard Geurts, Mark Opp, Daniel Zhang, Geoffrey Moros, Eduardo Feygelman, Vladimir |
author_sort | Stambaugh, Cassandra |
collection | PubMed |
description | It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed — on patient or phantom datasets — using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analysis of the agreement between the planned and delivered dose, including direct comparison of the dose‐volume histograms. While conceptually similar to modulated arc techniques, helical tomotherapy introduces significant challenges to the PDP formalism, arising primarily from TomoTherapy delivery dynamics. The temporal characteristics of the delivery are of the same order or shorter than the dosimeter's update interval (50 ms). Additionally, the prevalence of often small and complex segments, particularly with the 1 cm Y jaw setting, lead to challenges related to detector spacing. Here, we present and test a novel method of tomotherapy‐PDP (TPDP) designed to meet these challenges. One of the novel techniques introduced for TPDP is organization of the subbeams into larger subunits called sectors, which assures more robust synchronization of the measurement and delivery dynamics. Another important change is the optional application of a correction based on ion chamber (IC) measurements in the phantom. The TPDP method was validated by direct comparisons to the IC and an independent, biplanar diode array dosimeter previously evaluated for tomotherapy delivery quality assurance. Nineteen plans with varying complexity were analyzed for the 2.5 cm tomotherapy jaw setting and 18 for the 1 cm opening. The dose differences between the TPDP and IC were [Formula: see text] and [Formula: see text] , for 2.5 and 1.0 cm jaw plans, respectively. Gamma analysis agreement rates between TPDP and the independent array were: [Formula: see text] (using 3% global normalization/3 mm criteria) and [Formula: see text] (using 2% global/2 mm) for the 2.5 cm jaw plans; for 1 cm plans, they were [Formula: see text] (3% G/3) and [Formula: see text] (2% G/2). We conclude that TPDP is capable of volumetric dose reconstruction with acceptable accuracy. However, the challenges of fast tomotherapy delivery dynamics make TPDP less precise than the IMRT/VMAT PDP version, particularly for the 1 cm jaw setting. PACS number: 87.55Qr |
format | Online Article Text |
id | pubmed-5690083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56900832018-04-02 Measurement‐guided volumetric dose reconstruction for helical tomotherapy Stambaugh, Cassandra Nelms, Benjamin Wolf, Theresa Mueller, Richard Geurts, Mark Opp, Daniel Zhang, Geoffrey Moros, Eduardo Feygelman, Vladimir J Appl Clin Med Phys Radiation Oncology Physics It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed — on patient or phantom datasets — using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analysis of the agreement between the planned and delivered dose, including direct comparison of the dose‐volume histograms. While conceptually similar to modulated arc techniques, helical tomotherapy introduces significant challenges to the PDP formalism, arising primarily from TomoTherapy delivery dynamics. The temporal characteristics of the delivery are of the same order or shorter than the dosimeter's update interval (50 ms). Additionally, the prevalence of often small and complex segments, particularly with the 1 cm Y jaw setting, lead to challenges related to detector spacing. Here, we present and test a novel method of tomotherapy‐PDP (TPDP) designed to meet these challenges. One of the novel techniques introduced for TPDP is organization of the subbeams into larger subunits called sectors, which assures more robust synchronization of the measurement and delivery dynamics. Another important change is the optional application of a correction based on ion chamber (IC) measurements in the phantom. The TPDP method was validated by direct comparisons to the IC and an independent, biplanar diode array dosimeter previously evaluated for tomotherapy delivery quality assurance. Nineteen plans with varying complexity were analyzed for the 2.5 cm tomotherapy jaw setting and 18 for the 1 cm opening. The dose differences between the TPDP and IC were [Formula: see text] and [Formula: see text] , for 2.5 and 1.0 cm jaw plans, respectively. Gamma analysis agreement rates between TPDP and the independent array were: [Formula: see text] (using 3% global normalization/3 mm criteria) and [Formula: see text] (using 2% global/2 mm) for the 2.5 cm jaw plans; for 1 cm plans, they were [Formula: see text] (3% G/3) and [Formula: see text] (2% G/2). We conclude that TPDP is capable of volumetric dose reconstruction with acceptable accuracy. However, the challenges of fast tomotherapy delivery dynamics make TPDP less precise than the IMRT/VMAT PDP version, particularly for the 1 cm jaw setting. PACS number: 87.55Qr John Wiley and Sons Inc. 2015-03-08 /pmc/articles/PMC5690083/ /pubmed/26103199 http://dx.doi.org/10.1120/jacmp.v16i2.5298 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Stambaugh, Cassandra Nelms, Benjamin Wolf, Theresa Mueller, Richard Geurts, Mark Opp, Daniel Zhang, Geoffrey Moros, Eduardo Feygelman, Vladimir Measurement‐guided volumetric dose reconstruction for helical tomotherapy |
title | Measurement‐guided volumetric dose reconstruction for helical tomotherapy |
title_full | Measurement‐guided volumetric dose reconstruction for helical tomotherapy |
title_fullStr | Measurement‐guided volumetric dose reconstruction for helical tomotherapy |
title_full_unstemmed | Measurement‐guided volumetric dose reconstruction for helical tomotherapy |
title_short | Measurement‐guided volumetric dose reconstruction for helical tomotherapy |
title_sort | measurement‐guided volumetric dose reconstruction for helical tomotherapy |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690083/ https://www.ncbi.nlm.nih.gov/pubmed/26103199 http://dx.doi.org/10.1120/jacmp.v16i2.5298 |
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