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Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation

The purpose of this study was to describe our experience with 1.0T MR‐SIM including characterization, quality assurance (QA) program, and features necessary for treatment planning. Staffing, safety, and patient screening procedures were developed. Utilization of an external laser positioning system...

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Autores principales: Glide‐Hurst, Carri K., Wen, Ning, Hearshen, David, Kim, Joshua, Pantelic, Milan, Zhao, Bo, Mancell, Tina, Levin, Kenneth, Movsas, Benjamin, Chetty, Indrin J., Siddiqui, M. Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690096/
https://www.ncbi.nlm.nih.gov/pubmed/26103190
http://dx.doi.org/10.1120/jacmp.v16i2.5201
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author Glide‐Hurst, Carri K.
Wen, Ning
Hearshen, David
Kim, Joshua
Pantelic, Milan
Zhao, Bo
Mancell, Tina
Levin, Kenneth
Movsas, Benjamin
Chetty, Indrin J.
Siddiqui, M. Salim
author_facet Glide‐Hurst, Carri K.
Wen, Ning
Hearshen, David
Kim, Joshua
Pantelic, Milan
Zhao, Bo
Mancell, Tina
Levin, Kenneth
Movsas, Benjamin
Chetty, Indrin J.
Siddiqui, M. Salim
author_sort Glide‐Hurst, Carri K.
collection PubMed
description The purpose of this study was to describe our experience with 1.0T MR‐SIM including characterization, quality assurance (QA) program, and features necessary for treatment planning. Staffing, safety, and patient screening procedures were developed. Utilization of an external laser positioning system (ELPS) and MR‐compatible couchtop were illustrated. Spatial and volumetric analyses were conducted between CT‐SIM and MR‐SIM using a stereotactic QA phantom with known landmarks and volumes. Magnetic field inhomogeneity was determined using phase difference analysis. System‐related, in‐plane distortion was evaluated and temporal changes were assessed. 3D distortion was characterized for regions of interest (ROIs) [Formula: see text] away from isocenter. American College of Radiology (ACR) recommended tests and impact of ELPS on image quality were analyzed. Combined ultrashort echotime Dixon (UTE/Dixon) sequence was evaluated. Amplitude‐triggered 4D MRI was implemented using a motion phantom (2–10 phases, [Formula: see text] excursion, 3–5 s periods) and a liver cancer patient. Duty cycle, acquisition time, and excursion were evaluated between maximum intensity projection (MIP) datasets. Less than 2% difference from expected was obtained between CT‐SIM and MR‐SIM volumes, with a mean distance of [Formula: see text] between landmarks. Magnetic field inhomogeneity was [Formula: see text]. 2D distortion was [Formula: see text] over [Formula: see text] of isocenter. Within 5 cm radius of isocenter, mean 3D geometric distortion was [Formula: see text] ([Formula: see text]) and increased [Formula: see text] from isocenter ([Formula: see text] , [Formula: see text]). ELPS interference was within the operating frequency of the scanner and was characterized by line patterns and a reduction in signal‐to‐noise ratio (4.6–12.6% for [Formula: see text]). Image quality checks were within ACR recommendations. UTE/Dixon sequences yielded detectability between bone and air. For 4D MRI, faster breathing periods had higher duty cycles than slow (50.4% (3 s) and 39.4% (5 s), [Formula: see text]) and ~ fourfold acquisition time increase was measured for ten‐phase versus two‐phase. Superior–inferior object extent was underestimated 8% (6 mm) for two‐phase as compared to ten‐phase MIPs, although [Formula: see text] difference was obtained for [Formula: see text] phases. 4D MRI for a patient demonstrated acceptable image quality in [Formula: see text]. MR‐SIM was integrated into our workflow and QA procedures were developed. Clinical applicability was demonstrated for 4D MRI and UTE imaging to support MR‐SIM for single modality treatment planning. PACS numbers: 87.56.Fc, 87.61.‐c, 87.57.cp
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spelling pubmed-56900962018-04-02 Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation Glide‐Hurst, Carri K. Wen, Ning Hearshen, David Kim, Joshua Pantelic, Milan Zhao, Bo Mancell, Tina Levin, Kenneth Movsas, Benjamin Chetty, Indrin J. Siddiqui, M. Salim J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to describe our experience with 1.0T MR‐SIM including characterization, quality assurance (QA) program, and features necessary for treatment planning. Staffing, safety, and patient screening procedures were developed. Utilization of an external laser positioning system (ELPS) and MR‐compatible couchtop were illustrated. Spatial and volumetric analyses were conducted between CT‐SIM and MR‐SIM using a stereotactic QA phantom with known landmarks and volumes. Magnetic field inhomogeneity was determined using phase difference analysis. System‐related, in‐plane distortion was evaluated and temporal changes were assessed. 3D distortion was characterized for regions of interest (ROIs) [Formula: see text] away from isocenter. American College of Radiology (ACR) recommended tests and impact of ELPS on image quality were analyzed. Combined ultrashort echotime Dixon (UTE/Dixon) sequence was evaluated. Amplitude‐triggered 4D MRI was implemented using a motion phantom (2–10 phases, [Formula: see text] excursion, 3–5 s periods) and a liver cancer patient. Duty cycle, acquisition time, and excursion were evaluated between maximum intensity projection (MIP) datasets. Less than 2% difference from expected was obtained between CT‐SIM and MR‐SIM volumes, with a mean distance of [Formula: see text] between landmarks. Magnetic field inhomogeneity was [Formula: see text]. 2D distortion was [Formula: see text] over [Formula: see text] of isocenter. Within 5 cm radius of isocenter, mean 3D geometric distortion was [Formula: see text] ([Formula: see text]) and increased [Formula: see text] from isocenter ([Formula: see text] , [Formula: see text]). ELPS interference was within the operating frequency of the scanner and was characterized by line patterns and a reduction in signal‐to‐noise ratio (4.6–12.6% for [Formula: see text]). Image quality checks were within ACR recommendations. UTE/Dixon sequences yielded detectability between bone and air. For 4D MRI, faster breathing periods had higher duty cycles than slow (50.4% (3 s) and 39.4% (5 s), [Formula: see text]) and ~ fourfold acquisition time increase was measured for ten‐phase versus two‐phase. Superior–inferior object extent was underestimated 8% (6 mm) for two‐phase as compared to ten‐phase MIPs, although [Formula: see text] difference was obtained for [Formula: see text] phases. 4D MRI for a patient demonstrated acceptable image quality in [Formula: see text]. MR‐SIM was integrated into our workflow and QA procedures were developed. Clinical applicability was demonstrated for 4D MRI and UTE imaging to support MR‐SIM for single modality treatment planning. PACS numbers: 87.56.Fc, 87.61.‐c, 87.57.cp John Wiley and Sons Inc. 2015-03-08 /pmc/articles/PMC5690096/ /pubmed/26103190 http://dx.doi.org/10.1120/jacmp.v16i2.5201 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Glide‐Hurst, Carri K.
Wen, Ning
Hearshen, David
Kim, Joshua
Pantelic, Milan
Zhao, Bo
Mancell, Tina
Levin, Kenneth
Movsas, Benjamin
Chetty, Indrin J.
Siddiqui, M. Salim
Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation
title Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation
title_full Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation
title_fullStr Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation
title_full_unstemmed Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation
title_short Initial clinical experience with a radiation oncology dedicated open 1.0T MR‐simulation
title_sort initial clinical experience with a radiation oncology dedicated open 1.0t mr‐simulation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690096/
https://www.ncbi.nlm.nih.gov/pubmed/26103190
http://dx.doi.org/10.1120/jacmp.v16i2.5201
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