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Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group
This report describes the current state of flattening filter‐free (FFF) radiotherapy beams implemented on conventional linear accelerators, and is aimed primarily at practicing medical physicists. The Therapy Emerging Technology Assessment Work Group of the American Association of Physicists in Medi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690108/ https://www.ncbi.nlm.nih.gov/pubmed/26103482 http://dx.doi.org/10.1120/jacmp.v16i3.5219 |
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author | Xiao, Ying Kry, Stephen F. Popple, Richard Yorke, Ellen Papanikolaou, Niko Stathakis, Sotirios Xia, Ping Huq, Saiful Bayouth, John Galvin, James Yin, Fang‐Fang |
author_facet | Xiao, Ying Kry, Stephen F. Popple, Richard Yorke, Ellen Papanikolaou, Niko Stathakis, Sotirios Xia, Ping Huq, Saiful Bayouth, John Galvin, James Yin, Fang‐Fang |
author_sort | Xiao, Ying |
collection | PubMed |
description | This report describes the current state of flattening filter‐free (FFF) radiotherapy beams implemented on conventional linear accelerators, and is aimed primarily at practicing medical physicists. The Therapy Emerging Technology Assessment Work Group of the American Association of Physicists in Medicine (AAPM) formed a writing group to assess FFF technology. The published literature on FFF technology was reviewed, along with technical specifications provided by vendors. Based on this information, supplemented by the clinical experience of the group members, consensus guidelines and recommendations for implementation of FFF technology were developed. Areas in need of further investigation were identified. Removing the flattening filter increases beam intensity, especially near the central axis. Increased intensity reduces treatment time, especially for high‐dose stereotactic radiotherapy/radiosurgery (SRT/SRS). Furthermore, removing the flattening filter reduces out‐of‐field dose and improves beam modeling accuracy. FFF beams are advantageous for small field (e.g., SRS) treatments and are appropriate for intensity‐modulated radiotherapy (IMRT). For conventional 3D radiotherapy of large targets, FFF beams may be disadvantageous compared to flattened beams because of the heterogeneity of FFF beam across the target (unless modulation is employed). For any application, the nonflat beam characteristics and substantially higher dose rates require consideration during the commissioning and quality assurance processes relative to flattened beams, and the appropriate clinical use of the technology needs to be identified. Consideration also needs to be given to these unique characteristics when undertaking facility planning. Several areas still warrant further research and development. Recommendations pertinent to FFF technology, including acceptance testing, commissioning, quality assurance, radiation safety, and facility planning, are presented. Examples of clinical applications are provided. Several of the areas in which future research and development are needed are also indicated. PACS number: 87.53.‐j, 87.53.Bn, 87.53.Ly, 87.55.‐x, 87.55.N‐, 87.56.bc |
format | Online Article Text |
id | pubmed-5690108 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56901082018-04-02 Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group Xiao, Ying Kry, Stephen F. Popple, Richard Yorke, Ellen Papanikolaou, Niko Stathakis, Sotirios Xia, Ping Huq, Saiful Bayouth, John Galvin, James Yin, Fang‐Fang J Appl Clin Med Phys AAPM Reports & Documents This report describes the current state of flattening filter‐free (FFF) radiotherapy beams implemented on conventional linear accelerators, and is aimed primarily at practicing medical physicists. The Therapy Emerging Technology Assessment Work Group of the American Association of Physicists in Medicine (AAPM) formed a writing group to assess FFF technology. The published literature on FFF technology was reviewed, along with technical specifications provided by vendors. Based on this information, supplemented by the clinical experience of the group members, consensus guidelines and recommendations for implementation of FFF technology were developed. Areas in need of further investigation were identified. Removing the flattening filter increases beam intensity, especially near the central axis. Increased intensity reduces treatment time, especially for high‐dose stereotactic radiotherapy/radiosurgery (SRT/SRS). Furthermore, removing the flattening filter reduces out‐of‐field dose and improves beam modeling accuracy. FFF beams are advantageous for small field (e.g., SRS) treatments and are appropriate for intensity‐modulated radiotherapy (IMRT). For conventional 3D radiotherapy of large targets, FFF beams may be disadvantageous compared to flattened beams because of the heterogeneity of FFF beam across the target (unless modulation is employed). For any application, the nonflat beam characteristics and substantially higher dose rates require consideration during the commissioning and quality assurance processes relative to flattened beams, and the appropriate clinical use of the technology needs to be identified. Consideration also needs to be given to these unique characteristics when undertaking facility planning. Several areas still warrant further research and development. Recommendations pertinent to FFF technology, including acceptance testing, commissioning, quality assurance, radiation safety, and facility planning, are presented. Examples of clinical applications are provided. Several of the areas in which future research and development are needed are also indicated. PACS number: 87.53.‐j, 87.53.Bn, 87.53.Ly, 87.55.‐x, 87.55.N‐, 87.56.bc John Wiley and Sons Inc. 2015-05-08 /pmc/articles/PMC5690108/ /pubmed/26103482 http://dx.doi.org/10.1120/jacmp.v16i3.5219 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | AAPM Reports & Documents Xiao, Ying Kry, Stephen F. Popple, Richard Yorke, Ellen Papanikolaou, Niko Stathakis, Sotirios Xia, Ping Huq, Saiful Bayouth, John Galvin, James Yin, Fang‐Fang Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group |
title | Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group |
title_full | Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group |
title_fullStr | Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group |
title_full_unstemmed | Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group |
title_short | Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group |
title_sort | flattening filter‐free accelerators: a report from the aapm therapy emerging technology assessment work group |
topic | AAPM Reports & Documents |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690108/ https://www.ncbi.nlm.nih.gov/pubmed/26103482 http://dx.doi.org/10.1120/jacmp.v16i3.5219 |
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