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Modeling a superficial radiotherapy X‐ray source for relative dose calculations

The purpose of this study was to empirically characterize and validate a kilovoltage (kV) X‐ray beam source model of a superficial X‐ray unit for relative dose calculations in water and assess the accuracy of the British Journal of Radiology Supplement 25 (BJR 25) percentage depth dose (PDD) data. W...

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Autores principales: Johnstone, Christopher D., LaFontaine, Richard, Poirier, Yannick, Tambasco, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690109/
https://www.ncbi.nlm.nih.gov/pubmed/26103479
http://dx.doi.org/10.1120/jacmp.v16i3.5162
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author Johnstone, Christopher D.
LaFontaine, Richard
Poirier, Yannick
Tambasco, Mauro
author_facet Johnstone, Christopher D.
LaFontaine, Richard
Poirier, Yannick
Tambasco, Mauro
author_sort Johnstone, Christopher D.
collection PubMed
description The purpose of this study was to empirically characterize and validate a kilovoltage (kV) X‐ray beam source model of a superficial X‐ray unit for relative dose calculations in water and assess the accuracy of the British Journal of Radiology Supplement 25 (BJR 25) percentage depth dose (PDD) data. We measured central axis PDDs and dose profiles using an Xstrahl 150 X‐ray system. We also compared the measured and calculated PDDs to those in the BJR 25. The Xstrahl source was modeled as an effective point source with varying spatial fluence and spectra. In‐air ionization chamber measurements were made along the x‐ and y‐axes of the X‐ray beam to derive the spatial fluence and half‐value layer (HVL) measurements were made to derive the spatially varying spectra. This beam characterization and resulting source model was used as input for our in‐house dose calculation software (kVDoseCalc) to compute radiation dose at points of interest (POIs). The PDDs and dose profiles were measured using 2, 5, and 15 cm cone sizes at 80, 120, 140, and 150 kVp energies in a scanning water phantom using IBA Farmer‐type ionization chambers of volumes 0.65 and 0.13 cc, respectively. The percent difference in the computed PDDs compared with our measurements range from −4.8% to 4.8%, with an overall mean percent difference and standard deviation of 1.5% and 0.7%, respectively. The percent difference between our PDD measurements and those from BJR 25 range from −14.0% to 15.7%, with an overall mean percent difference and standard deviation of 4.9% and 2.1%, respectively — showing that the measurements are in much better agreement with kVDoseCalc than BJR 25. The range in percent difference between kVDoseCalc and measurement for profiles was −5.9% to 5.9%, with an overall mean percent difference and standard deviation of 1.4% and 1.4%, respectively. The results demonstrate that our empirically based X‐ray source modeling approach for superficial X‐ray therapy can be used to accurately compute relative dose in a homogeneous water‐equivalent medium. They also show limitations in the accuracy of the BJR 25 PDD data. PACS number: 87.55.kh
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spelling pubmed-56901092018-04-02 Modeling a superficial radiotherapy X‐ray source for relative dose calculations Johnstone, Christopher D. LaFontaine, Richard Poirier, Yannick Tambasco, Mauro J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to empirically characterize and validate a kilovoltage (kV) X‐ray beam source model of a superficial X‐ray unit for relative dose calculations in water and assess the accuracy of the British Journal of Radiology Supplement 25 (BJR 25) percentage depth dose (PDD) data. We measured central axis PDDs and dose profiles using an Xstrahl 150 X‐ray system. We also compared the measured and calculated PDDs to those in the BJR 25. The Xstrahl source was modeled as an effective point source with varying spatial fluence and spectra. In‐air ionization chamber measurements were made along the x‐ and y‐axes of the X‐ray beam to derive the spatial fluence and half‐value layer (HVL) measurements were made to derive the spatially varying spectra. This beam characterization and resulting source model was used as input for our in‐house dose calculation software (kVDoseCalc) to compute radiation dose at points of interest (POIs). The PDDs and dose profiles were measured using 2, 5, and 15 cm cone sizes at 80, 120, 140, and 150 kVp energies in a scanning water phantom using IBA Farmer‐type ionization chambers of volumes 0.65 and 0.13 cc, respectively. The percent difference in the computed PDDs compared with our measurements range from −4.8% to 4.8%, with an overall mean percent difference and standard deviation of 1.5% and 0.7%, respectively. The percent difference between our PDD measurements and those from BJR 25 range from −14.0% to 15.7%, with an overall mean percent difference and standard deviation of 4.9% and 2.1%, respectively — showing that the measurements are in much better agreement with kVDoseCalc than BJR 25. The range in percent difference between kVDoseCalc and measurement for profiles was −5.9% to 5.9%, with an overall mean percent difference and standard deviation of 1.4% and 1.4%, respectively. The results demonstrate that our empirically based X‐ray source modeling approach for superficial X‐ray therapy can be used to accurately compute relative dose in a homogeneous water‐equivalent medium. They also show limitations in the accuracy of the BJR 25 PDD data. PACS number: 87.55.kh John Wiley and Sons Inc. 2015-05-08 /pmc/articles/PMC5690109/ /pubmed/26103479 http://dx.doi.org/10.1120/jacmp.v16i3.5162 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Johnstone, Christopher D.
LaFontaine, Richard
Poirier, Yannick
Tambasco, Mauro
Modeling a superficial radiotherapy X‐ray source for relative dose calculations
title Modeling a superficial radiotherapy X‐ray source for relative dose calculations
title_full Modeling a superficial radiotherapy X‐ray source for relative dose calculations
title_fullStr Modeling a superficial radiotherapy X‐ray source for relative dose calculations
title_full_unstemmed Modeling a superficial radiotherapy X‐ray source for relative dose calculations
title_short Modeling a superficial radiotherapy X‐ray source for relative dose calculations
title_sort modeling a superficial radiotherapy x‐ray source for relative dose calculations
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690109/
https://www.ncbi.nlm.nih.gov/pubmed/26103479
http://dx.doi.org/10.1120/jacmp.v16i3.5162
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