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Potential of 3D printing technologies for fabrication of electron bolus and proton compensators

In electron and proton radiotherapy, applications of patient‐specific electron bolus or proton compensators during radiation treatments are often necessary to accommodate patient body surface irregularities, tissue inhomogeneity, and variations in PTV depths to achieve desired dose distributions. Em...

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Autores principales: Zou, Wei, Fisher, Ted, Zhang, Miao, Kim, Leonard, Chen, Ting, Narra, Venkat, Swann, Beth, Singh, Rachana, Siderit, Richard, Yin, Lingshu, Teo, Boon‐keng Kevin, Mckenna, Michael, McDonough, James, Ning, Yue J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690113/
https://www.ncbi.nlm.nih.gov/pubmed/26103473
http://dx.doi.org/10.1120/jacmp.v16i3.4959
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author Zou, Wei
Fisher, Ted
Zhang, Miao
Kim, Leonard
Chen, Ting
Narra, Venkat
Swann, Beth
Singh, Rachana
Siderit, Richard
Yin, Lingshu
Teo, Boon‐keng Kevin
Mckenna, Michael
McDonough, James
Ning, Yue J.
author_facet Zou, Wei
Fisher, Ted
Zhang, Miao
Kim, Leonard
Chen, Ting
Narra, Venkat
Swann, Beth
Singh, Rachana
Siderit, Richard
Yin, Lingshu
Teo, Boon‐keng Kevin
Mckenna, Michael
McDonough, James
Ning, Yue J.
author_sort Zou, Wei
collection PubMed
description In electron and proton radiotherapy, applications of patient‐specific electron bolus or proton compensators during radiation treatments are often necessary to accommodate patient body surface irregularities, tissue inhomogeneity, and variations in PTV depths to achieve desired dose distributions. Emerging 3D printing technologies provide alternative fabrication methods for these bolus and compensators. This study investigated the potential of utilizing 3D printing technologies for the fabrication of the electron bolus and proton compensators. Two printing technologies, fused deposition modeling (FDM) and selective laser sintering (SLS), and two printing materials, PLA and polyamide, were investigated. Samples were printed and characterized with CT scan and under electron and proton beams. In addition, a software package was developed to convert electron bolus and proton compensator designs to printable Standard Tessellation Language file format. A phantom scalp electron bolus was printed with FDM technology with PLA material. The HU of the printed electron bolus was [Formula: see text]. A prostate patient proton compensator was printed with SLS technology and polyamide material with [Formula: see text] HU. The profiles of the electron bolus and proton compensator were compared with the original designs. The average over all the CT slices of the largest Euclidean distance between the design and the fabricated bolus on each CT slice was found to be [Formula: see text] and for the compensator to be [Formula: see text]. It is recommended that the properties of specific 3D printed objects are understood before being applied to radiotherapy treatments. PACS number: 81.40
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spelling pubmed-56901132018-04-02 Potential of 3D printing technologies for fabrication of electron bolus and proton compensators Zou, Wei Fisher, Ted Zhang, Miao Kim, Leonard Chen, Ting Narra, Venkat Swann, Beth Singh, Rachana Siderit, Richard Yin, Lingshu Teo, Boon‐keng Kevin Mckenna, Michael McDonough, James Ning, Yue J. J Appl Clin Med Phys Radiation Oncology Physics In electron and proton radiotherapy, applications of patient‐specific electron bolus or proton compensators during radiation treatments are often necessary to accommodate patient body surface irregularities, tissue inhomogeneity, and variations in PTV depths to achieve desired dose distributions. Emerging 3D printing technologies provide alternative fabrication methods for these bolus and compensators. This study investigated the potential of utilizing 3D printing technologies for the fabrication of the electron bolus and proton compensators. Two printing technologies, fused deposition modeling (FDM) and selective laser sintering (SLS), and two printing materials, PLA and polyamide, were investigated. Samples were printed and characterized with CT scan and under electron and proton beams. In addition, a software package was developed to convert electron bolus and proton compensator designs to printable Standard Tessellation Language file format. A phantom scalp electron bolus was printed with FDM technology with PLA material. The HU of the printed electron bolus was [Formula: see text]. A prostate patient proton compensator was printed with SLS technology and polyamide material with [Formula: see text] HU. The profiles of the electron bolus and proton compensator were compared with the original designs. The average over all the CT slices of the largest Euclidean distance between the design and the fabricated bolus on each CT slice was found to be [Formula: see text] and for the compensator to be [Formula: see text]. It is recommended that the properties of specific 3D printed objects are understood before being applied to radiotherapy treatments. PACS number: 81.40 John Wiley and Sons Inc. 2015-05-08 /pmc/articles/PMC5690113/ /pubmed/26103473 http://dx.doi.org/10.1120/jacmp.v16i3.4959 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Zou, Wei
Fisher, Ted
Zhang, Miao
Kim, Leonard
Chen, Ting
Narra, Venkat
Swann, Beth
Singh, Rachana
Siderit, Richard
Yin, Lingshu
Teo, Boon‐keng Kevin
Mckenna, Michael
McDonough, James
Ning, Yue J.
Potential of 3D printing technologies for fabrication of electron bolus and proton compensators
title Potential of 3D printing technologies for fabrication of electron bolus and proton compensators
title_full Potential of 3D printing technologies for fabrication of electron bolus and proton compensators
title_fullStr Potential of 3D printing technologies for fabrication of electron bolus and proton compensators
title_full_unstemmed Potential of 3D printing technologies for fabrication of electron bolus and proton compensators
title_short Potential of 3D printing technologies for fabrication of electron bolus and proton compensators
title_sort potential of 3d printing technologies for fabrication of electron bolus and proton compensators
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690113/
https://www.ncbi.nlm.nih.gov/pubmed/26103473
http://dx.doi.org/10.1120/jacmp.v16i3.4959
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