Cargando…
Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment
The purpose of this study was to evaluate the accuracy of commercially available software, using patient DVH‐based QA metrics, by investigating the correlation between estimated 3D patient dose and magnitude of MLC misalignments. We tested 3DVH software with an ArcCHECK. Two different calculating mo...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690121/ https://www.ncbi.nlm.nih.gov/pubmed/26103486 http://dx.doi.org/10.1120/jacmp.v16i3.5251 |
_version_ | 1783279534627356672 |
---|---|
author | Kadoya, Noriyuki Saito, Masahide Ogasawara, Makoto Fujita, Yukio Ito, Kengo Sato, Kiyokazu Kishi, Kazuma Dobashi, Suguru Takeda, Ken Jingu, Keiichi |
author_facet | Kadoya, Noriyuki Saito, Masahide Ogasawara, Makoto Fujita, Yukio Ito, Kengo Sato, Kiyokazu Kishi, Kazuma Dobashi, Suguru Takeda, Ken Jingu, Keiichi |
author_sort | Kadoya, Noriyuki |
collection | PubMed |
description | The purpose of this study was to evaluate the accuracy of commercially available software, using patient DVH‐based QA metrics, by investigating the correlation between estimated 3D patient dose and magnitude of MLC misalignments. We tested 3DVH software with an ArcCHECK. Two different calculating modes of ArcCHECK Planned Dose Perturbation (ACPDP) were used: “Normal Sensitivity” and “High Sensitivity”. Ten prostate cancer patients treated with hypofractionated VMAT (67.6 Gy/26 Fr) in our hospital were studied. For the baseline plan, we induced MLC errors ([Formula: see text] , and 0.75 mm for each single bank). We calculated the dose differences between the ACPDP dose with error and TPS dose with error using gamma passing rates and using DVH‐based QA metrics. The correlations between dose estimation error and MLC position error varied with each structure and metric. A comparison using [Formula: see text] gamma index showed that the larger was the MLC error‐induced, the worse were the gamma passing rates. Slopes of linear fit to dose estimation error versus MLC position error for mean dose and D95 to the PTV were 1.76 and [Formula: see text] , respectively, for “Normal Sensitivity”, and −0.53 and [Formula: see text] , respectively, for “High Sensitivity”, showing better accuracy for “High Sensitivity” than “Normal Sensitivity”. On the other hand, the slopes for mean dose to the rectum and bladder, V35 to the rectum and bladder and V55 to the rectum and bladder, were [Formula: see text] , and [Formula: see text] , respectively, for “Normal Sensitivity”, and [Formula: see text] , and [Formula: see text] , respectively, for “High Sensitivity”, showing significant better accuracy for “Normal Sensitivity” than “High Sensitivity”. Our results showed that 3DVH had some residual error for both sensitivities. Furthermore, we found that “Normal Sensitivity” might have better accuracy for the DVH metric for the PTV and that “High Sensitivity” might have better accuracy for DVH metrics for the rectum and bladder. We must be willing to tolerate this residual error in clinical care. PACS number: 87.55Qr |
format | Online Article Text |
id | pubmed-5690121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56901212018-04-02 Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment Kadoya, Noriyuki Saito, Masahide Ogasawara, Makoto Fujita, Yukio Ito, Kengo Sato, Kiyokazu Kishi, Kazuma Dobashi, Suguru Takeda, Ken Jingu, Keiichi J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to evaluate the accuracy of commercially available software, using patient DVH‐based QA metrics, by investigating the correlation between estimated 3D patient dose and magnitude of MLC misalignments. We tested 3DVH software with an ArcCHECK. Two different calculating modes of ArcCHECK Planned Dose Perturbation (ACPDP) were used: “Normal Sensitivity” and “High Sensitivity”. Ten prostate cancer patients treated with hypofractionated VMAT (67.6 Gy/26 Fr) in our hospital were studied. For the baseline plan, we induced MLC errors ([Formula: see text] , and 0.75 mm for each single bank). We calculated the dose differences between the ACPDP dose with error and TPS dose with error using gamma passing rates and using DVH‐based QA metrics. The correlations between dose estimation error and MLC position error varied with each structure and metric. A comparison using [Formula: see text] gamma index showed that the larger was the MLC error‐induced, the worse were the gamma passing rates. Slopes of linear fit to dose estimation error versus MLC position error for mean dose and D95 to the PTV were 1.76 and [Formula: see text] , respectively, for “Normal Sensitivity”, and −0.53 and [Formula: see text] , respectively, for “High Sensitivity”, showing better accuracy for “High Sensitivity” than “Normal Sensitivity”. On the other hand, the slopes for mean dose to the rectum and bladder, V35 to the rectum and bladder and V55 to the rectum and bladder, were [Formula: see text] , and [Formula: see text] , respectively, for “Normal Sensitivity”, and [Formula: see text] , and [Formula: see text] , respectively, for “High Sensitivity”, showing significant better accuracy for “Normal Sensitivity” than “High Sensitivity”. Our results showed that 3DVH had some residual error for both sensitivities. Furthermore, we found that “Normal Sensitivity” might have better accuracy for the DVH metric for the PTV and that “High Sensitivity” might have better accuracy for DVH metrics for the rectum and bladder. We must be willing to tolerate this residual error in clinical care. PACS number: 87.55Qr John Wiley and Sons Inc. 2015-05-08 /pmc/articles/PMC5690121/ /pubmed/26103486 http://dx.doi.org/10.1120/jacmp.v16i3.5251 Text en © 2015 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Kadoya, Noriyuki Saito, Masahide Ogasawara, Makoto Fujita, Yukio Ito, Kengo Sato, Kiyokazu Kishi, Kazuma Dobashi, Suguru Takeda, Ken Jingu, Keiichi Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment |
title | Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment |
title_full | Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment |
title_fullStr | Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment |
title_full_unstemmed | Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment |
title_short | Evaluation of patient DVH‐based QA metrics for prostate VMAT: correlation between accuracy of estimated 3D patient dose and magnitude of MLC misalignment |
title_sort | evaluation of patient dvh‐based qa metrics for prostate vmat: correlation between accuracy of estimated 3d patient dose and magnitude of mlc misalignment |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690121/ https://www.ncbi.nlm.nih.gov/pubmed/26103486 http://dx.doi.org/10.1120/jacmp.v16i3.5251 |
work_keys_str_mv | AT kadoyanoriyuki evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT saitomasahide evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT ogasawaramakoto evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT fujitayukio evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT itokengo evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT satokiyokazu evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT kishikazuma evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT dobashisuguru evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT takedaken evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment AT jingukeiichi evaluationofpatientdvhbasedqametricsforprostatevmatcorrelationbetweenaccuracyofestimated3dpatientdoseandmagnitudeofmlcmisalignment |