Cargando…

Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance

The need to accurately and efficiently verify both output and dose profiles creates significant challenges in quality assurance of pencil beam scanning (PBS) proton delivery. A system for PBS QA has been developed that combines a new two‐dimensional ionization chamber array in a waterproof housing t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Liyong, Kang, Minglei, Solberg, Timothy D., Mertens, Thierry, Baumer, Christian, Ainsley, Christopher G., McDonough, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690130/
https://www.ncbi.nlm.nih.gov/pubmed/26103492
http://dx.doi.org/10.1120/jacmp.v16i3.5323
_version_ 1783279536800006144
author Lin, Liyong
Kang, Minglei
Solberg, Timothy D.
Mertens, Thierry
Baumer, Christian
Ainsley, Christopher G.
McDonough, James E.
author_facet Lin, Liyong
Kang, Minglei
Solberg, Timothy D.
Mertens, Thierry
Baumer, Christian
Ainsley, Christopher G.
McDonough, James E.
author_sort Lin, Liyong
collection PubMed
description The need to accurately and efficiently verify both output and dose profiles creates significant challenges in quality assurance of pencil beam scanning (PBS) proton delivery. A system for PBS QA has been developed that combines a new two‐dimensional ionization chamber array in a waterproof housing that is scanned in a water phantom. The MatriXX PT has the same detector array arrangement as the standard [Formula: see text] but utilizes a smaller 2 mm plate spacing instead of 5 mm. Because the bias voltage of the MatriXX PT and Evolution cannot be changed, PPC40 and FC65‐G ionization chambers were used to assess recombination effects. The PPC40 is a parallel plate chamber with an electrode spacing of 2 mm, while the FC65‐G is a Farmer chamber FC65‐G with an electrode spacing of 2.8 mm. Three bias voltages (500, 200, and 100 V) were used for both detectors to determine which radiation type (continuous, pulse or pulse‐scanned beam) could closely estimate [Formula: see text] from the ratios of charges collected. In comparison with the [Formula: see text] , a significant improvement in measurement of absolute dose with the MatriXX PT was observed. While dose uncertainty of the [Formula: see text] can be up to 4%, it is [Formula: see text] for the MatriXX PT. Therefore the [Formula: see text] should not be used for QA of PBS for conditions in which ion recombination is not negligible. Farmer chambers should be used with caution for measuring the absolute dose of PBS beams, as the uncertainty of [Formula: see text] can be [Formula: see text]; chambers with an electrode spacing of 2 mm or smaller are recommended. PACS number: 87.53.Qc
format Online
Article
Text
id pubmed-5690130
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-56901302018-04-02 Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance Lin, Liyong Kang, Minglei Solberg, Timothy D. Mertens, Thierry Baumer, Christian Ainsley, Christopher G. McDonough, James E. J Appl Clin Med Phys Radiation Oncology Physics The need to accurately and efficiently verify both output and dose profiles creates significant challenges in quality assurance of pencil beam scanning (PBS) proton delivery. A system for PBS QA has been developed that combines a new two‐dimensional ionization chamber array in a waterproof housing that is scanned in a water phantom. The MatriXX PT has the same detector array arrangement as the standard [Formula: see text] but utilizes a smaller 2 mm plate spacing instead of 5 mm. Because the bias voltage of the MatriXX PT and Evolution cannot be changed, PPC40 and FC65‐G ionization chambers were used to assess recombination effects. The PPC40 is a parallel plate chamber with an electrode spacing of 2 mm, while the FC65‐G is a Farmer chamber FC65‐G with an electrode spacing of 2.8 mm. Three bias voltages (500, 200, and 100 V) were used for both detectors to determine which radiation type (continuous, pulse or pulse‐scanned beam) could closely estimate [Formula: see text] from the ratios of charges collected. In comparison with the [Formula: see text] , a significant improvement in measurement of absolute dose with the MatriXX PT was observed. While dose uncertainty of the [Formula: see text] can be up to 4%, it is [Formula: see text] for the MatriXX PT. Therefore the [Formula: see text] should not be used for QA of PBS for conditions in which ion recombination is not negligible. Farmer chambers should be used with caution for measuring the absolute dose of PBS beams, as the uncertainty of [Formula: see text] can be [Formula: see text]; chambers with an electrode spacing of 2 mm or smaller are recommended. PACS number: 87.53.Qc John Wiley and Sons Inc. 2015-05-08 /pmc/articles/PMC5690130/ /pubmed/26103492 http://dx.doi.org/10.1120/jacmp.v16i3.5323 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Lin, Liyong
Kang, Minglei
Solberg, Timothy D.
Mertens, Thierry
Baumer, Christian
Ainsley, Christopher G.
McDonough, James E.
Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
title Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
title_full Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
title_fullStr Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
title_full_unstemmed Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
title_short Use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
title_sort use of a novel two‐dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690130/
https://www.ncbi.nlm.nih.gov/pubmed/26103492
http://dx.doi.org/10.1120/jacmp.v16i3.5323
work_keys_str_mv AT linliyong useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance
AT kangminglei useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance
AT solbergtimothyd useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance
AT mertensthierry useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance
AT baumerchristian useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance
AT ainsleychristopherg useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance
AT mcdonoughjamese useofanoveltwodimensionalionizationchamberarrayforpencilbeamscanningprotontherapybeamqualityassurance