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Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation

TomoDirect (TD) is an intensity‐modulated radiotherapy system that uses a fixed gantry angle instead of rotational beam delivery. Here, we investigated the effect of the multiple beam technique of TomoDirect on dose distribution compared with commonly‐used tangential beams. We included 45 consecutiv...

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Autores principales: Hashimoto, Harumitsu, Omura, Motoko, Matsui, Kengo, Mukai, Yuki, Hongo, Hideyuki, Yamakabe, Wataru, Saito, Kaori, Yoshida, Miwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690132/
https://www.ncbi.nlm.nih.gov/pubmed/26103495
http://dx.doi.org/10.1120/jacmp.v16i3.5369
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author Hashimoto, Harumitsu
Omura, Motoko
Matsui, Kengo
Mukai, Yuki
Hongo, Hideyuki
Yamakabe, Wataru
Saito, Kaori
Yoshida, Miwa
author_facet Hashimoto, Harumitsu
Omura, Motoko
Matsui, Kengo
Mukai, Yuki
Hongo, Hideyuki
Yamakabe, Wataru
Saito, Kaori
Yoshida, Miwa
author_sort Hashimoto, Harumitsu
collection PubMed
description TomoDirect (TD) is an intensity‐modulated radiotherapy system that uses a fixed gantry angle instead of rotational beam delivery. Here, we investigated the effect of the multiple beam technique of TomoDirect on dose distribution compared with commonly‐used tangential beams. We included 45 consecutive patients with right breast cancer who underwent postoperative radiotherapy in our institute in the present study. Clinical target volume (CTV) was the whole right breast. The planning target volume (PTV) was created by expanding the CTV by a 0.5 cm margin. Paired TD plans were generated for each patient; a two‐beam plan using paired tangential beams and a six‐beam plan with four additional beams with modified gantry angles of [Formula: see text] from the original tangential beam set. A prescribed dose of 50 Gy was defined for 50% isodoses of the PTV. The six‐beam plan delivered significantly more homogeneous doses to the PTV than the two‐beam plan; and the mean dose to the PTV in the six‐beam plan more closely reflected the prescribed dose. [Formula: see text] and mean dose to the right lung and mean dose to the whole body were also significantly decreased in the six‐beam plan. However, duration of radiation exposure was 1 min longer in the six‐beam plan than in the two‐beam plan. The dose distribution to the target and organs at risk were improved with the six‐beam plan relative to the two‐beam plan without increasing the whole‐body radiation dose. The six‐beam plan using TD is a simple technique that can be routinely applied to whole‐breast irradiation in clinical practice. PACS number: 87.55
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spelling pubmed-56901322018-04-02 Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation Hashimoto, Harumitsu Omura, Motoko Matsui, Kengo Mukai, Yuki Hongo, Hideyuki Yamakabe, Wataru Saito, Kaori Yoshida, Miwa J Appl Clin Med Phys Radiation Oncology Physics TomoDirect (TD) is an intensity‐modulated radiotherapy system that uses a fixed gantry angle instead of rotational beam delivery. Here, we investigated the effect of the multiple beam technique of TomoDirect on dose distribution compared with commonly‐used tangential beams. We included 45 consecutive patients with right breast cancer who underwent postoperative radiotherapy in our institute in the present study. Clinical target volume (CTV) was the whole right breast. The planning target volume (PTV) was created by expanding the CTV by a 0.5 cm margin. Paired TD plans were generated for each patient; a two‐beam plan using paired tangential beams and a six‐beam plan with four additional beams with modified gantry angles of [Formula: see text] from the original tangential beam set. A prescribed dose of 50 Gy was defined for 50% isodoses of the PTV. The six‐beam plan delivered significantly more homogeneous doses to the PTV than the two‐beam plan; and the mean dose to the PTV in the six‐beam plan more closely reflected the prescribed dose. [Formula: see text] and mean dose to the right lung and mean dose to the whole body were also significantly decreased in the six‐beam plan. However, duration of radiation exposure was 1 min longer in the six‐beam plan than in the two‐beam plan. The dose distribution to the target and organs at risk were improved with the six‐beam plan relative to the two‐beam plan without increasing the whole‐body radiation dose. The six‐beam plan using TD is a simple technique that can be routinely applied to whole‐breast irradiation in clinical practice. PACS number: 87.55 John Wiley and Sons Inc. 2015-05-08 /pmc/articles/PMC5690132/ /pubmed/26103495 http://dx.doi.org/10.1120/jacmp.v16i3.5369 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Hashimoto, Harumitsu
Omura, Motoko
Matsui, Kengo
Mukai, Yuki
Hongo, Hideyuki
Yamakabe, Wataru
Saito, Kaori
Yoshida, Miwa
Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation
title Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation
title_full Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation
title_fullStr Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation
title_full_unstemmed Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation
title_short Tangent field technique of TomoDirect improves dose distribution for whole‐breast irradiation
title_sort tangent field technique of tomodirect improves dose distribution for whole‐breast irradiation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690132/
https://www.ncbi.nlm.nih.gov/pubmed/26103495
http://dx.doi.org/10.1120/jacmp.v16i3.5369
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