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Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery

Permanent implant of sealed radioactive sources is an effective technique for treating cancer. Typically, the radioactive sources are implanted in and near the disease, depositing radiation absorbed dose locally over several months. There may be instances where these patients must undergo unrelated...

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Autores principales: Basran, Parminder S., Baxter, Patricia, Beckham, Wayne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690180/
https://www.ncbi.nlm.nih.gov/pubmed/26699296
http://dx.doi.org/10.1120/jacmp.v16i5.5372
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author Basran, Parminder S.
Baxter, Patricia
Beckham, Wayne A.
author_facet Basran, Parminder S.
Baxter, Patricia
Beckham, Wayne A.
author_sort Basran, Parminder S.
collection PubMed
description Permanent implant of sealed radioactive sources is an effective technique for treating cancer. Typically, the radioactive sources are implanted in and near the disease, depositing radiation absorbed dose locally over several months. There may be instances where these patients must undergo unrelated surgical procedures when the radioactive material remains active enough to pose risks. This work explores these risks, discusses strategies to mitigate those risks, and describes a case study for a permanent iodine‐125 (I‐125) prostate brachytherapy implant patient who developed colorectal cancer and required surgery six months after brachytherapy. The first consideration is identifying the radiological risk to the patient and staff before, during, and after the surgical procedure. The second is identifying the risk the surgical procedure may have on the efficacy of the brachytherapy implant. Finally, there are considerations for controlling the radioactive substances from a regulatory perspective. After these risks are defined, strategies to mitigate those risks are considered. We summarize this experience with some guidelines: If the surgical procedure is near (e.g., within 5–10 cm of) the implant; and, the surgical intervention may dislodge sources enough to compromise treatment or introduces radiation safety risks; and, the radioactivity has not sufficiently decayed to background levels; and, the surgery cannot be postponed, then a detailed analysis of risk is advised. PACS numbers: 87.53Bn, 87.53Jw, 87.55.N, 87.56.bg
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spelling pubmed-56901802018-04-02 Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery Basran, Parminder S. Baxter, Patricia Beckham, Wayne A. J Appl Clin Med Phys Radiation Oncology Physics Permanent implant of sealed radioactive sources is an effective technique for treating cancer. Typically, the radioactive sources are implanted in and near the disease, depositing radiation absorbed dose locally over several months. There may be instances where these patients must undergo unrelated surgical procedures when the radioactive material remains active enough to pose risks. This work explores these risks, discusses strategies to mitigate those risks, and describes a case study for a permanent iodine‐125 (I‐125) prostate brachytherapy implant patient who developed colorectal cancer and required surgery six months after brachytherapy. The first consideration is identifying the radiological risk to the patient and staff before, during, and after the surgical procedure. The second is identifying the risk the surgical procedure may have on the efficacy of the brachytherapy implant. Finally, there are considerations for controlling the radioactive substances from a regulatory perspective. After these risks are defined, strategies to mitigate those risks are considered. We summarize this experience with some guidelines: If the surgical procedure is near (e.g., within 5–10 cm of) the implant; and, the surgical intervention may dislodge sources enough to compromise treatment or introduces radiation safety risks; and, the radioactivity has not sufficiently decayed to background levels; and, the surgery cannot be postponed, then a detailed analysis of risk is advised. PACS numbers: 87.53Bn, 87.53Jw, 87.55.N, 87.56.bg John Wiley and Sons Inc. 2015-09-08 /pmc/articles/PMC5690180/ /pubmed/26699296 http://dx.doi.org/10.1120/jacmp.v16i5.5372 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Basran, Parminder S.
Baxter, Patricia
Beckham, Wayne A.
Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
title Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
title_full Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
title_fullStr Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
title_full_unstemmed Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
title_short Reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
title_sort reducing radiation risks to staff for patients with permanently implanted radioactive sources requiring unrelated surgery
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690180/
https://www.ncbi.nlm.nih.gov/pubmed/26699296
http://dx.doi.org/10.1120/jacmp.v16i5.5372
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