Cargando…

Anti-inflammatory effects of hypoxia-preconditioned human periodontal ligament cell secretome in an experimental model of multiple sclerosis: a key role of IL-37

Recent research has widely investigated the anti-inflammatory effects of mesenchymal stem cells and their secretory products, termed the secretome, in the treatment of multiple sclerosis (MS). The present study examined the capacity of the conditioned medium (CM) from human periodontal ligament stem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giacoppo, Sabrina, Thangavelu, Soundara Rajan, Diomede, Francesca, Bramanti, Placido, Conti, Pio, Trubiani, Oriana, Mazzon, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690382/ https://www.ncbi.nlm.nih.gov/pubmed/28842429 http://dx.doi.org/10.1096/fj.201700524R

Ejemplares similares

Human periodontal ligament stem cells secretome from multiple sclerosis patients suppresses NALP3 inflammasome activation in experimental autoimmune encephalomyelitis
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2017)

The secretome of periodontal ligament stem cells from MS patients protects against EAE
por: Rajan, Thangavelu Soundara, et al.
Publicado: (2016)

Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: Role of epigenetic modifications to the inflammation
por: Diomede, Francesca, et al.
Publicado: (2017)

Conditioned medium from human gingival mesenchymal stem cells protects motor-neuron-like NSC-34 cells against scratch-injury-induced cell death
por: Rajan, Thangavelu Soundara, et al.
Publicado: (2017)

Stemness Characteristics of Periodontal Ligament Stem Cells from Donors and Multiple Sclerosis Patients: A Comparative Study
por: Diomede, Francesca, et al.
Publicado: (2017)

Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis
por: Trubiani, Oriana, et al.
Publicado: (2016)

Physiological Expression of Ion Channel Receptors in Human Periodontal Ligament Stem Cells
por: Chiricosta, Luigi, et al.
Publicado: (2019)

Oral Bone Tissue Regeneration: Mesenchymal Stem Cells, Secretome, and Biomaterials
por: Gugliandolo, Agnese, et al.
Publicado: (2021)

Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
por: Libro, Rosaliana, et al.
Publicado: (2016)

The Role of Hypoxia on the Neuronal Differentiation of Gingival Mesenchymal Stem Cells: A Transcriptional Study
por: Gugliandolo, Agnese, et al.
Publicado: (2019)

Moringin Pretreatment Inhibits the Expression of Genes Involved in Mitophagy in the Stem Cell of the Human Periodontal Ligament
por: Chiricosta, Luigi, et al.
Publicado: (2019)

Moringin Induces Neural Differentiation in the Stem Cell of the Human Periodontal Ligament
por: Romeo, Letizia, et al.
Publicado: (2018)

Engineered Extracellular Vesicles From Human Periodontal-Ligament Stem Cells Increase VEGF/VEGFR2 Expression During Bone Regeneration
por: Pizzicannella, Jacopo, et al.
Publicado: (2019)

Addendum: Engineered extracellular vesicles from human periodontal-ligament stem cells increase VEGF/VEGFR2 expression during bone regeneration
por: Pizzicannella, Jacopo, et al.
Publicado: (2023)

Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage
por: Diomede, Francesca, et al.
Publicado: (2017)

Human Periodontal Ligament Stem Cells Response to Titanium Implant Surface: Extracellular Matrix Deposition
por: Marconi, Guya Diletta, et al.
Publicado: (2021)

Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis
por: Giacoppo, Sabrina, et al.
Publicado: (2016)

Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway
por: Lanza Cariccio, Veronica, et al.
Publicado: (2018)

In Vitro-Transcribed mRNA Chimeric Antigen Receptor T Cell (IVT mRNA CAR T) Therapy in Hematologic and Solid Tumor Management: A Preclinical Update
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2020)

Tunneling Nanotubes-Mediated Protection of Mesenchymal Stem Cells: An Update from Preclinical Studies
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2020)

Correction: Marconi et al. Human Periodontal Ligament Stem Cells Response to Titanium Implant Surface: Extracellular Matrix Deposition. Biology 2021, 10, 931
por: Marconi, Guya Diletta, et al.
Publicado: (2023)

Cannabinoid CB2 Receptors are Involved in the Protection of RAW264.7 Macrophages Against the Oxidative Stress: An in Vitro Study
por: Giacoppo, Sabrina, et al.
Publicado: (2017)

Potential Anti-Inflammatory Effects of a New Lyophilized Formulation of the Conditioned Medium Derived from Periodontal Ligament Stem Cells
por: Gugliandolo, Agnese, et al.
Publicado: (2022)

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis
por: Chiricosta, Luigi, et al.
Publicado: (2020)

Hypoxia: molecular pathophysiological mechanisms in human diseases
por: Della Rocca, Ylenia, et al.
Publicado: (2022)

Transcriptomic Analysis of Stem Cells Treated with Moringin or Cannabidiol: Analogies and Differences in Inflammation Pathways
por: Chiricosta, Luigi, et al.
Publicado: (2019)

A novel role in skeletal segment regeneration of extracellular vesicles released from periodontal-ligament stem cells
por: Diomede, Francesca, et al.
Publicado: (2018)

Stem Cells Therapy for Spinal Cord Injury: An Overview of Clinical Trials
por: Silvestro, Serena, et al.
Publicado: (2020)

Extracellular Vesicles Derived from Human Gingival Mesenchymal Stem Cells: A Transcriptomic Analysis
por: Silvestro, Serena, et al.
Publicado: (2020)

MicroRNA Profiling of HL-1 Cardiac Cells-Derived Extracellular Vesicles
por: Silvestro, Serena, et al.
Publicado: (2021)

Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration
por: Diomede, Francesca, et al.
Publicado: (2020)

Salivary Biomarkers: Future Approaches for Early Diagnosis of Neurodegenerative Diseases
por: Schepici, Giovanni, et al.
Publicado: (2020)

Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
por: Libro, Rosaliana, et al.
Publicado: (2016)

3D Printing PLA/Gingival Stem Cells/ EVs Upregulate miR-2861 and -210 during Osteoangiogenesis Commitment
por: Pizzicannella, Jacopo, et al.
Publicado: (2019)

Triggering of inflammasome by impaired autophagy in response to acute experimental Parkinson’s disease: involvement of the PI3K/Akt/mTOR pathway
por: Giacoppo, Sabrina, et al.
Publicado: (2017)

Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFκB/Caspase-1/IL-1β Pathway
por: Pizzicannella, Jacopo, et al.
Publicado: (2021)

Inhibition of LPS-Induced Inflammatory Response of Oral Mesenchymal Stem Cells in the Presence of Galectin-3
por: Paganelli, Alessia, et al.
Publicado: (2023)

Enhanced VEGF/VEGF-R and RUNX2 Expression in Human Periodontal Ligament Stem Cells Cultured on Sandblasted/Etched Titanium Disk
por: Marconi, Guya Diletta, et al.
Publicado: (2020)

Epithelial-Mesenchymal Transition (EMT): The Type-2 EMT in Wound Healing, Tissue Regeneration and Organ Fibrosis
por: Marconi, Guya D., et al.
Publicado: (2021)

Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells
por: Libro, Rosaliana, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9is63lt851ba4gdi7gcj55gjp4