A dynamic ribosomal biogenesis response is not required for IGF-1–mediated hypertrophy of human primary myotubes

Increased ribosomal DNA transcription has been proposed to limit muscle protein synthesis, making ribosome biogenesis central to skeletal muscle hypertrophy. We examined the relationship between ribosomal RNA (rRNA) production and IGF-1–mediated myotube hypertrophy in vitro. Primary skeletal myotube...

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Detalles Bibliográficos
Autores principales: Crossland, Hannah, Timmons, James A., Atherton, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690393/
https://www.ncbi.nlm.nih.gov/pubmed/28774889
http://dx.doi.org/10.1096/fj.201700329R

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