RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines

Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which relates to the pathogenesis of DENV infection. However, how DENV induced liver injury is not fully understood. In this study, we aim to identi...

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Detalles Bibliográficos
Autores principales: Morchang, Atthapan, Lee, Regina Ching Hua, Yenchitsomanus, Pa-thai, Sreekanth, Gopinathan Pillai, Noisakran, Sansanee, Chu, Justin Jang Hann, Limjindaporn, Thawornchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690425/
https://www.ncbi.nlm.nih.gov/pubmed/29145490
http://dx.doi.org/10.1371/journal.pone.0188121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690425/
https://www.ncbi.nlm.nih.gov/pubmed/29145490
http://dx.doi.org/10.1371/journal.pone.0188121

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