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RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines
Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which relates to the pathogenesis of DENV infection. However, how DENV induced liver injury is not fully understood. In this study, we aim to identi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690425/ https://www.ncbi.nlm.nih.gov/pubmed/29145490 http://dx.doi.org/10.1371/journal.pone.0188121 |