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EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams

We proposed to perform a basic dosimetry commissioning on a new imager system, the Varian aS1200 electronic portal imaging device (EPID) and TrueBeam 2.0 linear accelerator for flattened (FF) and flattening filter‐free (FFF) beams, then to develop an image‐based quality assurance (QA) model for veri...

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Detalles Bibliográficos
Autores principales: Miri, Narges, Keller, Peter, Zwan, Benjamin J., Greer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690494/
https://www.ncbi.nlm.nih.gov/pubmed/27929502
http://dx.doi.org/10.1120/jacmp.v17i6.6336
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author Miri, Narges
Keller, Peter
Zwan, Benjamin J.
Greer, Peter
author_facet Miri, Narges
Keller, Peter
Zwan, Benjamin J.
Greer, Peter
author_sort Miri, Narges
collection PubMed
description We proposed to perform a basic dosimetry commissioning on a new imager system, the Varian aS1200 electronic portal imaging device (EPID) and TrueBeam 2.0 linear accelerator for flattened (FF) and flattening filter‐free (FFF) beams, then to develop an image‐based quality assurance (QA) model for verification of the system delivery accuracy for intensity‐modulated radiation therapy (IMRT) treatments. For dosimetry testing, linearity of dose response with MU, imager lag, and effectiveness of backscatter shielding were investigated. Then, an image‐based model was developed to convert images to planar dose onto a virtual water phantom. The model parameters were identified using energy fluence of the Acuros treatment planning system (TPS) and, reference dose profiles and output factors measured at depths of 5, 10, 15, and 20 cm in water phantom for square fields. To validate the model, its calculated dose was compared to measured dose from MapCHECK 2 diode arrays for 36 IMRT fields at 10 cm depth delivered with 6X, 6XFFF, 10X, and 10XFFF energies. An in‐house gamma function was used to compare planar doses pixel‐by‐pixel. Finally, the method was applied to the same IMRT fields to verify their pretreatment delivery dose compared with Eclipse TPS dose. For the EPID commissioning, dose linearity was within 0.4% above 5 MU and [Formula: see text] above 2 MU, measured lag was smaller than the previous EPIDs, and profile symmetry was improved. The model was validated with mean gamma pass rates (standard deviation) of 99.0% (0.4%), 99.5% (0.6%), 99.3% (0.4%), and 98.0% (0.8%) at 3%/3 mm for respectively 6X, 6XFFF, 10X, and 10XFFF beams. Using the same comparison criteria, the beam deliveries were verified with mean pass rates of 100% (0.0%), 99.6% (0.3%), 99.9% (0.1%), and 98.7% (1.4%). Improvements were observed in dosimetric response of the aS1200 imager compared to previous EPID models, and the model was successfully developed for the new system and delivery energies of 6 and 10 MV, FF, and FFF modes. PACS number(s): 87.53.Oq, 87.53.Xd
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spelling pubmed-56904942018-04-02 EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams Miri, Narges Keller, Peter Zwan, Benjamin J. Greer, Peter J Appl Clin Med Phys Radiation Oncology Physics We proposed to perform a basic dosimetry commissioning on a new imager system, the Varian aS1200 electronic portal imaging device (EPID) and TrueBeam 2.0 linear accelerator for flattened (FF) and flattening filter‐free (FFF) beams, then to develop an image‐based quality assurance (QA) model for verification of the system delivery accuracy for intensity‐modulated radiation therapy (IMRT) treatments. For dosimetry testing, linearity of dose response with MU, imager lag, and effectiveness of backscatter shielding were investigated. Then, an image‐based model was developed to convert images to planar dose onto a virtual water phantom. The model parameters were identified using energy fluence of the Acuros treatment planning system (TPS) and, reference dose profiles and output factors measured at depths of 5, 10, 15, and 20 cm in water phantom for square fields. To validate the model, its calculated dose was compared to measured dose from MapCHECK 2 diode arrays for 36 IMRT fields at 10 cm depth delivered with 6X, 6XFFF, 10X, and 10XFFF energies. An in‐house gamma function was used to compare planar doses pixel‐by‐pixel. Finally, the method was applied to the same IMRT fields to verify their pretreatment delivery dose compared with Eclipse TPS dose. For the EPID commissioning, dose linearity was within 0.4% above 5 MU and [Formula: see text] above 2 MU, measured lag was smaller than the previous EPIDs, and profile symmetry was improved. The model was validated with mean gamma pass rates (standard deviation) of 99.0% (0.4%), 99.5% (0.6%), 99.3% (0.4%), and 98.0% (0.8%) at 3%/3 mm for respectively 6X, 6XFFF, 10X, and 10XFFF beams. Using the same comparison criteria, the beam deliveries were verified with mean pass rates of 100% (0.0%), 99.6% (0.3%), 99.9% (0.1%), and 98.7% (1.4%). Improvements were observed in dosimetric response of the aS1200 imager compared to previous EPID models, and the model was successfully developed for the new system and delivery energies of 6 and 10 MV, FF, and FFF modes. PACS number(s): 87.53.Oq, 87.53.Xd John Wiley and Sons Inc. 2016-11-08 /pmc/articles/PMC5690494/ /pubmed/27929502 http://dx.doi.org/10.1120/jacmp.v17i6.6336 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Miri, Narges
Keller, Peter
Zwan, Benjamin J.
Greer, Peter
EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams
title EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams
title_full EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams
title_fullStr EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams
title_full_unstemmed EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams
title_short EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams
title_sort epid‐based dosimetry to verify imrt planar dose distribution for the as1200 epid and fff beams
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690494/
https://www.ncbi.nlm.nih.gov/pubmed/27929502
http://dx.doi.org/10.1120/jacmp.v17i6.6336
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