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TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models
BACKGROUND AND OBJECTIVES: Vascular calcification (VC) is a major risk factor for elevated cardiovascular morbidity/mortality. Underlying this process is osteoblastic signalling within the vessel wall involving complex and interlinked roles for receptor-activator of nuclear factor-κB ligand (RANKL),...
Autores principales: | Harper, Emma, Rochfort, Keith D., Forde, Hannah, Davenport, Colin, Smith, Diarmuid, Cummins, Philip M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690591/ https://www.ncbi.nlm.nih.gov/pubmed/29145460 http://dx.doi.org/10.1371/journal.pone.0188192 |
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