Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity

A major challenge is to understand maladaptive changes in ion channels that sets neurons on a course towards epilepsy development. Voltage- and calcium-activated K+ (BK) channels contribute to early spike timing in neurons, and studies indicate that the BK channel plays a pathological role in increa...

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Detalles Bibliográficos
Autores principales: Whitmire, Luke E., Ling, Ling, Bugay, Vladslav, Carver, Chase M., Timilsina, Santosh, Chuang, Hui-Hsiu, Jaffe, David B., Shapiro, Mark S., Cavazos, Jose E., Brenner, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690595/
https://www.ncbi.nlm.nih.gov/pubmed/29145442
http://dx.doi.org/10.1371/journal.pone.0188064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690595/
https://www.ncbi.nlm.nih.gov/pubmed/29145442
http://dx.doi.org/10.1371/journal.pone.0188064

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