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Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity
A major challenge is to understand maladaptive changes in ion channels that sets neurons on a course towards epilepsy development. Voltage- and calcium-activated K+ (BK) channels contribute to early spike timing in neurons, and studies indicate that the BK channel plays a pathological role in increa...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690595/ https://www.ncbi.nlm.nih.gov/pubmed/29145442 http://dx.doi.org/10.1371/journal.pone.0188064 |