Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide

θ-defensins constitute a family of macrocyclic peptides expressed exclusively in Old World monkeys. The peptides are pleiotropic effectors of innate immunity, possessing broad spectrum antimicrobial activities and immunoregulatory properties. Here we report that rhesus θ-defensin 1 (RTD-1) is highly...

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Detalles Bibliográficos
Autores principales: Schaal, Justin B., Tran, Dat Q., Subramanian, Akshay, Patel, Reshma, Laragione, Teresina, Roberts, Kevin D., Trinh, Katie, Tongaonkar, Prasad, Tran, Patti A., Minond, Dmitriy, Fields, Gregg B., Beringer, Paul, Ouellette, André J., Gulko, Percio S., Selsted, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690597/
https://www.ncbi.nlm.nih.gov/pubmed/29145473
http://dx.doi.org/10.1371/journal.pone.0187868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690597/
https://www.ncbi.nlm.nih.gov/pubmed/29145473
http://dx.doi.org/10.1371/journal.pone.0187868

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