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Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles

Nanoparticles represent promising gene delivery systems in biomedicine to facilitate prolonged gene expression with low toxicity compared to viral vectors. Specifically, nanoparticles of calcium phosphate (nCaP), the main inorganic component of human bone, exhibit high biocompatibility and good biod...

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Detalles Bibliográficos
Autores principales: Vanegas Sáenz, Juan Ramón, Tenkumo, Taichi, Kamano, Yuya, Egusa, Hiroshi, Sasaki, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690608/
https://www.ncbi.nlm.nih.gov/pubmed/29145481
http://dx.doi.org/10.1371/journal.pone.0188347