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Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon

Cervical cancer (CC) is the most common type of cancer in women and is the third leading cause of death in most developing countries, causing more than 288,000 deaths in women worldwide each year. The most favourable survival rate is in developed countries, since CC mortality has recently declined i...

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Autores principales: Carneiro, Saul Rassy, Fagundes, Marcela de Araújo, do Rosário, Pricila de Jesus Oliveira, Neves, Laura Maria Tomazi., Souza, Givago da Silva, Pinheiro, Maria da Conceição Nascimento
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690614/
https://www.ncbi.nlm.nih.gov/pubmed/29145414
http://dx.doi.org/10.1371/journal.pone.0187579
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author Carneiro, Saul Rassy
Fagundes, Marcela de Araújo
do Rosário, Pricila de Jesus Oliveira
Neves, Laura Maria Tomazi.
Souza, Givago da Silva
Pinheiro, Maria da Conceição Nascimento
author_facet Carneiro, Saul Rassy
Fagundes, Marcela de Araújo
do Rosário, Pricila de Jesus Oliveira
Neves, Laura Maria Tomazi.
Souza, Givago da Silva
Pinheiro, Maria da Conceição Nascimento
author_sort Carneiro, Saul Rassy
collection PubMed
description Cervical cancer (CC) is the most common type of cancer in women and is the third leading cause of death in most developing countries, causing more than 288,000 deaths in women worldwide each year. The most favourable survival rate is in developed countries, since CC mortality has recently declined in those countries. The purpose of this study was to determine the survival rate and associated factors of CC patients at a reference hospital in the Amazon region. The patient sample included records of 339 patients with cervical cancer who had been hospitalized in Belém, Pará, Brazil from January 2005 to December 2010; the socioeconomic and clinical data were collected between June and September 2016. A survival rate of approximately 84% was observed, and it was found that disease stage (p <0.01), metastasis (p <0.01) and readmission (p <0.01) had significant influences on patient outcome. The impact of these factors on the general survival rate was higher in the Amazon region compared with other regions of Brazil, and the primary survival factors were associated with earlier stages of the disease. However, more national studies are needed on this subject. Our findings may contribute to the development of regional strategies for the prevention of cervical cancer, a reduction in its incidence and mortality rate, an increase in survival time and an improvement in the quality of life of these women.
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spelling pubmed-56906142017-11-30 Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon Carneiro, Saul Rassy Fagundes, Marcela de Araújo do Rosário, Pricila de Jesus Oliveira Neves, Laura Maria Tomazi. Souza, Givago da Silva Pinheiro, Maria da Conceição Nascimento PLoS One Research Article Cervical cancer (CC) is the most common type of cancer in women and is the third leading cause of death in most developing countries, causing more than 288,000 deaths in women worldwide each year. The most favourable survival rate is in developed countries, since CC mortality has recently declined in those countries. The purpose of this study was to determine the survival rate and associated factors of CC patients at a reference hospital in the Amazon region. The patient sample included records of 339 patients with cervical cancer who had been hospitalized in Belém, Pará, Brazil from January 2005 to December 2010; the socioeconomic and clinical data were collected between June and September 2016. A survival rate of approximately 84% was observed, and it was found that disease stage (p <0.01), metastasis (p <0.01) and readmission (p <0.01) had significant influences on patient outcome. The impact of these factors on the general survival rate was higher in the Amazon region compared with other regions of Brazil, and the primary survival factors were associated with earlier stages of the disease. However, more national studies are needed on this subject. Our findings may contribute to the development of regional strategies for the prevention of cervical cancer, a reduction in its incidence and mortality rate, an increase in survival time and an improvement in the quality of life of these women. Public Library of Science 2017-11-16 /pmc/articles/PMC5690614/ /pubmed/29145414 http://dx.doi.org/10.1371/journal.pone.0187579 Text en © 2017 Carneiro et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Carneiro, Saul Rassy
Fagundes, Marcela de Araújo
do Rosário, Pricila de Jesus Oliveira
Neves, Laura Maria Tomazi.
Souza, Givago da Silva
Pinheiro, Maria da Conceição Nascimento
Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon
title Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon
title_full Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon
title_fullStr Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon
title_full_unstemmed Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon
title_short Five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the Brazilian Amazon
title_sort five-year survival and associated factors in women treated for cervical cancer at a reference hospital in the brazilian amazon
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690614/
https://www.ncbi.nlm.nih.gov/pubmed/29145414
http://dx.doi.org/10.1371/journal.pone.0187579
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