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Predictors of suicide ideation among older adults with bipolar disorder

OBJECTIVES: Bipolar disorder (BD) carries the greatest risk of death by suicide of all psychiatric conditions as 25%–50% of those with BD will make one or more suicide attempt, and about 15% will intentionally end their lives. Among young adults with BD, substance misuse, medication non-adherence, a...

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Autores principales: O’Rourke, Norm, Heisel, Marnin J., Canham, Sarah L., Sixsmith, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690620/
https://www.ncbi.nlm.nih.gov/pubmed/29145409
http://dx.doi.org/10.1371/journal.pone.0187632
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author O’Rourke, Norm
Heisel, Marnin J.
Canham, Sarah L.
Sixsmith, Andrew
author_facet O’Rourke, Norm
Heisel, Marnin J.
Canham, Sarah L.
Sixsmith, Andrew
author_sort O’Rourke, Norm
collection PubMed
description OBJECTIVES: Bipolar disorder (BD) carries the greatest risk of death by suicide of all psychiatric conditions as 25%–50% of those with BD will make one or more suicide attempt, and about 15% will intentionally end their lives. Among young adults with BD, substance misuse, medication non-adherence, age at onset, and comorbid psychiatric conditions each predict self-harm. It is currently unclear if these same factors or others predict suicide ideation among older adults with BD. METHODS: We recruited a global sample of 220 older adults with BD over 19 days using socio-demographically targeted, social media advertising and online data collection (Mean = 58.50, SD = 5.42; range 50 to 81 years). Path analyses allowed us to identify direct and indirect predictors of suicide ideation among older adults with BD. RESULTS: Cognitive failures (perception, memory, and motor function), depressive symptoms, alcohol misuse, and dissatisfaction with life as direct predictors of suicide ideation; duration of BD symptoms and medication non-adherence emerged as indirect predictors. Of note, the significant impact of sleep on suicide ideation is indirect via depressive symptoms, cognitive failures, medication non-adherence and life dissatisfaction. CONCLUSIONS: As with young adults with BD, alcohol misuse and medication non-adherence emerged as significant predictors of suicide ideation. In addition, cognitive failures directly and indirectly predict suicide ideation in this sample of older adults with BD. Population aging and treatment efficacy are leading to ever growing numbers of older adults with BD. Both direct and indirect predictors of suicide ideation need to be considered in future BD research and treatment planning.
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spelling pubmed-56906202017-11-30 Predictors of suicide ideation among older adults with bipolar disorder O’Rourke, Norm Heisel, Marnin J. Canham, Sarah L. Sixsmith, Andrew PLoS One Research Article OBJECTIVES: Bipolar disorder (BD) carries the greatest risk of death by suicide of all psychiatric conditions as 25%–50% of those with BD will make one or more suicide attempt, and about 15% will intentionally end their lives. Among young adults with BD, substance misuse, medication non-adherence, age at onset, and comorbid psychiatric conditions each predict self-harm. It is currently unclear if these same factors or others predict suicide ideation among older adults with BD. METHODS: We recruited a global sample of 220 older adults with BD over 19 days using socio-demographically targeted, social media advertising and online data collection (Mean = 58.50, SD = 5.42; range 50 to 81 years). Path analyses allowed us to identify direct and indirect predictors of suicide ideation among older adults with BD. RESULTS: Cognitive failures (perception, memory, and motor function), depressive symptoms, alcohol misuse, and dissatisfaction with life as direct predictors of suicide ideation; duration of BD symptoms and medication non-adherence emerged as indirect predictors. Of note, the significant impact of sleep on suicide ideation is indirect via depressive symptoms, cognitive failures, medication non-adherence and life dissatisfaction. CONCLUSIONS: As with young adults with BD, alcohol misuse and medication non-adherence emerged as significant predictors of suicide ideation. In addition, cognitive failures directly and indirectly predict suicide ideation in this sample of older adults with BD. Population aging and treatment efficacy are leading to ever growing numbers of older adults with BD. Both direct and indirect predictors of suicide ideation need to be considered in future BD research and treatment planning. Public Library of Science 2017-11-16 /pmc/articles/PMC5690620/ /pubmed/29145409 http://dx.doi.org/10.1371/journal.pone.0187632 Text en © 2017 O’Rourke et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
O’Rourke, Norm
Heisel, Marnin J.
Canham, Sarah L.
Sixsmith, Andrew
Predictors of suicide ideation among older adults with bipolar disorder
title Predictors of suicide ideation among older adults with bipolar disorder
title_full Predictors of suicide ideation among older adults with bipolar disorder
title_fullStr Predictors of suicide ideation among older adults with bipolar disorder
title_full_unstemmed Predictors of suicide ideation among older adults with bipolar disorder
title_short Predictors of suicide ideation among older adults with bipolar disorder
title_sort predictors of suicide ideation among older adults with bipolar disorder
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690620/
https://www.ncbi.nlm.nih.gov/pubmed/29145409
http://dx.doi.org/10.1371/journal.pone.0187632
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