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Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform

Cell death induced by excessive glutamate receptor overactivation, excitotoxicity, has been implicated in several acute and chronic neurological disorders. While numerous studies have demonstrated the contribution of biochemically and genetically activated cell death pathways in excitotoxic injury,...

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Detalles Bibliográficos
Autores principales: Anilkumar, Ujval, Weisova, Petronela, Schmid, Jasmin, Bernas, Tytus, Huber, Heinrich J., Düssmann, Heiko, Connolly, Niamh M. C., Prehn, Jochen H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690623/
https://www.ncbi.nlm.nih.gov/pubmed/29145487
http://dx.doi.org/10.1371/journal.pone.0188343