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Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform
Cell death induced by excessive glutamate receptor overactivation, excitotoxicity, has been implicated in several acute and chronic neurological disorders. While numerous studies have demonstrated the contribution of biochemically and genetically activated cell death pathways in excitotoxic injury,...
Autores principales: | Anilkumar, Ujval, Weisova, Petronela, Schmid, Jasmin, Bernas, Tytus, Huber, Heinrich J., Düssmann, Heiko, Connolly, Niamh M. C., Prehn, Jochen H. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690623/ https://www.ncbi.nlm.nih.gov/pubmed/29145487 http://dx.doi.org/10.1371/journal.pone.0188343 |
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