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Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT(2A) and 5-HT(2B) receptors in chondrocytes

Serotonin (5-hydroxytryptamine: 5-HT) is recognized as a neurotransmitter in the central nerve system and as a regulator of systemic blood pressure in the peripheral tissues. Recently, it was reported that 5-HT(2) receptors (5-HT(2)Rs) were expressed in cartilage tissues lacking both vessels and neu...

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Detalles Bibliográficos
Autores principales: Hori, Ayaka, Nishida, Takashi, Takashiba, Shogo, Kubota, Satoshi, Takigawa, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690650/
https://www.ncbi.nlm.nih.gov/pubmed/29145495
http://dx.doi.org/10.1371/journal.pone.0188014