Stochastic loss and gain of symmetric divisions in the C. elegans epidermis perturbs robustness of stem cell number

Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate phenotypic variability, what their relationship i...

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Detalles Bibliográficos
Autores principales: Katsanos, Dimitris, Koneru, Sneha L., Mestek Boukhibar, Lamia, Gritti, Nicola, Ghose, Ritobrata, Appleford, Peter J., Doitsidou, Maria, Woollard, Alison, van Zon, Jeroen S., Poole, Richard J., Barkoulas, Michalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690688/
https://www.ncbi.nlm.nih.gov/pubmed/29108019
http://dx.doi.org/10.1371/journal.pbio.2002429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690688/
https://www.ncbi.nlm.nih.gov/pubmed/29108019
http://dx.doi.org/10.1371/journal.pbio.2002429

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