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Stochastic loss and gain of symmetric divisions in the C. elegans epidermis perturbs robustness of stem cell number
Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate phenotypic variability, what their relationship i...
Autores principales: | Katsanos, Dimitris, Koneru, Sneha L., Mestek Boukhibar, Lamia, Gritti, Nicola, Ghose, Ritobrata, Appleford, Peter J., Doitsidou, Maria, Woollard, Alison, van Zon, Jeroen S., Poole, Richard J., Barkoulas, Michalis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690688/ https://www.ncbi.nlm.nih.gov/pubmed/29108019 http://dx.doi.org/10.1371/journal.pbio.2002429 |
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