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Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
RATIONALE: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS: We report the case of a 59-year-old woman who presented with Garci...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690742/ https://www.ncbi.nlm.nih.gov/pubmed/29137049 http://dx.doi.org/10.1097/MD.0000000000008508 |
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author | Xia, Nian-ge Chen, Yan-yan Wang, Xin-shi Xu, Hui-qin Zheng, Rong-yuan |
author_facet | Xia, Nian-ge Chen, Yan-yan Wang, Xin-shi Xu, Hui-qin Zheng, Rong-yuan |
author_sort | Xia, Nian-ge |
collection | PubMed |
description | RATIONALE: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS: We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years. DIAGNOSIS: A left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis. INTERVENTIONS: The patient was treated 3 times with local-field palliative radiotherapy. OUTCOMES: She died after several months. LESSONS: To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome. |
format | Online Article Text |
id | pubmed-5690742 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-56907422017-11-28 Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report Xia, Nian-ge Chen, Yan-yan Wang, Xin-shi Xu, Hui-qin Zheng, Rong-yuan Medicine (Baltimore) 5300 RATIONALE: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS: We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years. DIAGNOSIS: A left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis. INTERVENTIONS: The patient was treated 3 times with local-field palliative radiotherapy. OUTCOMES: She died after several months. LESSONS: To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome. Wolters Kluwer Health 2017-11-10 /pmc/articles/PMC5690742/ /pubmed/29137049 http://dx.doi.org/10.1097/MD.0000000000008508 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | 5300 Xia, Nian-ge Chen, Yan-yan Wang, Xin-shi Xu, Hui-qin Zheng, Rong-yuan Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report |
title | Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report |
title_full | Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report |
title_fullStr | Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report |
title_full_unstemmed | Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report |
title_short | Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report |
title_sort | garcin syndrome caused by parotid gland adenoid cystic carcinoma: a case report |
topic | 5300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690742/ https://www.ncbi.nlm.nih.gov/pubmed/29137049 http://dx.doi.org/10.1097/MD.0000000000008508 |
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