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Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report

RATIONALE: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS: We report the case of a 59-year-old woman who presented with Garci...

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Autores principales: Xia, Nian-ge, Chen, Yan-yan, Wang, Xin-shi, Xu, Hui-qin, Zheng, Rong-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690742/
https://www.ncbi.nlm.nih.gov/pubmed/29137049
http://dx.doi.org/10.1097/MD.0000000000008508
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author Xia, Nian-ge
Chen, Yan-yan
Wang, Xin-shi
Xu, Hui-qin
Zheng, Rong-yuan
author_facet Xia, Nian-ge
Chen, Yan-yan
Wang, Xin-shi
Xu, Hui-qin
Zheng, Rong-yuan
author_sort Xia, Nian-ge
collection PubMed
description RATIONALE: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS: We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years. DIAGNOSIS: A left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis. INTERVENTIONS: The patient was treated 3 times with local-field palliative radiotherapy. OUTCOMES: She died after several months. LESSONS: To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome.
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spelling pubmed-56907422017-11-28 Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report Xia, Nian-ge Chen, Yan-yan Wang, Xin-shi Xu, Hui-qin Zheng, Rong-yuan Medicine (Baltimore) 5300 RATIONALE: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS: We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years. DIAGNOSIS: A left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis. INTERVENTIONS: The patient was treated 3 times with local-field palliative radiotherapy. OUTCOMES: She died after several months. LESSONS: To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome. Wolters Kluwer Health 2017-11-10 /pmc/articles/PMC5690742/ /pubmed/29137049 http://dx.doi.org/10.1097/MD.0000000000008508 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 5300
Xia, Nian-ge
Chen, Yan-yan
Wang, Xin-shi
Xu, Hui-qin
Zheng, Rong-yuan
Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
title Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
title_full Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
title_fullStr Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
title_full_unstemmed Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
title_short Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report
title_sort garcin syndrome caused by parotid gland adenoid cystic carcinoma: a case report
topic 5300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690742/
https://www.ncbi.nlm.nih.gov/pubmed/29137049
http://dx.doi.org/10.1097/MD.0000000000008508
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