Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma

Malignant mesothelioma (MM) is an aggressive malignancy, highly resistant to current medical and surgical therapies, whose tumor cells characteristically show a high level of aneuploidy and genomic instability. We tested our hypothesis that targeting chromosomal instability in MM would improve respo...

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Detalles Bibliográficos
Autores principales: Szymiczek, Agata, Carbone, Michele, Pastorino, Sandra, Napolitano, Andrea, Tanji, Mika, Minaai, Michael, Pagano, Ian, Mason, Jacqueline M., Pass, Harvey I., Bray, Mark R., Mak, Tak W., Yang, Haining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690838/
https://www.ncbi.nlm.nih.gov/pubmed/28759042
http://dx.doi.org/10.1038/onc.2017.266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690838/
https://www.ncbi.nlm.nih.gov/pubmed/28759042
http://dx.doi.org/10.1038/onc.2017.266

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