Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia

Obesity is associated with an increase in cancer-specific mortality in women with breast cancer. Elevated cholesterol, particularly low-density lipoprotein cholesterol (LDL-C) is frequently seen in obese women. Here, we aimed to determine the importance of elevated circulating LDL, and LDL receptor...

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Detalles Bibliográficos
Autores principales: Gallagher, Emily J., Zelenko, Zara, Neel, Brian M., Antoniou, Irini M., Rajan, Laya, Kase, Nathan, LeRoith., Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690879/
https://www.ncbi.nlm.nih.gov/pubmed/28759039
http://dx.doi.org/10.1038/onc.2017.247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690879/
https://www.ncbi.nlm.nih.gov/pubmed/28759039
http://dx.doi.org/10.1038/onc.2017.247

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