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PET imaging of dopamine-D2 receptor internalization in schizophrenia

Recent genetic, molecular and postmortem studies suggest impaired D2R trafficking in patients with schizophrenia (SZ). Imaging and preclinical studies have shown agonist-induced D2R internalization can be imaged with positron emission tomography (PET) using dopamine-D2 receptor (D2R) radiotracers co...

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Detalles Bibliográficos
Autores principales: Weinstein, Jodi J., van de Giessen, Elsmarieke, Rosengard, Rachel J., Xu, Xiaoyan, Ojeil, Najate, Brucato, Gary, Gil, Roberto B., Kegeles, Lawrence S., Laruelle, Marc, Slifstein, Mark, Abi-Dargham, Anissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690884/
https://www.ncbi.nlm.nih.gov/pubmed/28507321
http://dx.doi.org/10.1038/mp.2017.107