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Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI

Our institution performs in vivo verification measurement for each of our total body irradiation (TBI) patients with optically stimulated luminescent dosimeters (OSLD). The lung block verification measurements were commonly higher than expected. The aim of this work is to understand this discrepancy...

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Autores principales: Narayanasamy, Ganesh, Cruz, Wilbert, Saenz, Daniel L., Stathakis, Sotirios, Papanikolaou, Niko, Kirby, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690919/
https://www.ncbi.nlm.nih.gov/pubmed/27167290
http://dx.doi.org/10.1120/jacmp.v17i3.6128
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author Narayanasamy, Ganesh
Cruz, Wilbert
Saenz, Daniel L.
Stathakis, Sotirios
Papanikolaou, Niko
Kirby, Neil
author_facet Narayanasamy, Ganesh
Cruz, Wilbert
Saenz, Daniel L.
Stathakis, Sotirios
Papanikolaou, Niko
Kirby, Neil
author_sort Narayanasamy, Ganesh
collection PubMed
description Our institution performs in vivo verification measurement for each of our total body irradiation (TBI) patients with optically stimulated luminescent dosimeters (OSLD). The lung block verification measurements were commonly higher than expected. The aim of this work is to understand this discrepancy and improve the accuracy of these lung block verification measurements. Initially, the thickness of the lung block was increased to provide adequate lung sparing. Further tests revealed the increase was due to electron contamination dose emanating from the lung block. The thickness of the bolus material covering the OSLD behind the lung block was increased to offset the electron contamination. In addition, the distance from the lung block to the dosimeter was evaluated for its effect on the OSLD reading and found to be clinically insignificant over the range of variability in our clinic. The results show that the improved TBI treatment technique provides for better accuracy of measured dose in vivo and consistency of patient setup. PACS number(s): 87.53.Bn, 87.53.Kn, 87.55.N‐, 87.55.Qr
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spelling pubmed-56909192018-04-02 Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI Narayanasamy, Ganesh Cruz, Wilbert Saenz, Daniel L. Stathakis, Sotirios Papanikolaou, Niko Kirby, Neil J Appl Clin Med Phys Radiation Measurements Our institution performs in vivo verification measurement for each of our total body irradiation (TBI) patients with optically stimulated luminescent dosimeters (OSLD). The lung block verification measurements were commonly higher than expected. The aim of this work is to understand this discrepancy and improve the accuracy of these lung block verification measurements. Initially, the thickness of the lung block was increased to provide adequate lung sparing. Further tests revealed the increase was due to electron contamination dose emanating from the lung block. The thickness of the bolus material covering the OSLD behind the lung block was increased to offset the electron contamination. In addition, the distance from the lung block to the dosimeter was evaluated for its effect on the OSLD reading and found to be clinically insignificant over the range of variability in our clinic. The results show that the improved TBI treatment technique provides for better accuracy of measured dose in vivo and consistency of patient setup. PACS number(s): 87.53.Bn, 87.53.Kn, 87.55.N‐, 87.55.Qr John Wiley and Sons Inc. 2016-05-08 /pmc/articles/PMC5690919/ /pubmed/27167290 http://dx.doi.org/10.1120/jacmp.v17i3.6128 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Measurements
Narayanasamy, Ganesh
Cruz, Wilbert
Saenz, Daniel L.
Stathakis, Sotirios
Papanikolaou, Niko
Kirby, Neil
Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI
title Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI
title_full Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI
title_fullStr Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI
title_full_unstemmed Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI
title_short Effect of electron contamination on in vivo dosimetry for lung block shielding during TBI
title_sort effect of electron contamination on in vivo dosimetry for lung block shielding during tbi
topic Radiation Measurements
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690919/
https://www.ncbi.nlm.nih.gov/pubmed/27167290
http://dx.doi.org/10.1120/jacmp.v17i3.6128
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