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Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams

This study investigated the impact of beam complexities on planar quality assurance and plan quality robustness by introducing MLC errors in intensity‐modulate radiation therapy. Forty patients' planar quality assurance (QA) plans were enrolled in this study, including 20 dynamic MLC (DMLC) IMR...

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Autores principales: Wang, Jiazhou, Jin, Xiance, Peng, Jiayuan, Xie, Jiang, Chen, Junchao, Hu, Weigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690928/
https://www.ncbi.nlm.nih.gov/pubmed/27167272
http://dx.doi.org/10.1120/jacmp.v17i3.6022
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author Wang, Jiazhou
Jin, Xiance
Peng, Jiayuan
Xie, Jiang
Chen, Junchao
Hu, Weigang
author_facet Wang, Jiazhou
Jin, Xiance
Peng, Jiayuan
Xie, Jiang
Chen, Junchao
Hu, Weigang
author_sort Wang, Jiazhou
collection PubMed
description This study investigated the impact of beam complexities on planar quality assurance and plan quality robustness by introducing MLC errors in intensity‐modulate radiation therapy. Forty patients' planar quality assurance (QA) plans were enrolled in this study, including 20 dynamic MLC (DMLC) IMRT plans and 20 static MLC (SMLC) IMRT plans. The total beam numbers were 150 and 160 for DMLC and SMLC, respectively. Six different magnitudes of MLC errors were introduced to these beams. Gamma pass rates were calculated by comparing error‐free fluence and error‐induced fluence. The plan quality variation was acquired by comparing PTV coverage. Eight complexity scores were calculated based on the beam fluence and the MLC sequence. The complexity scores include fractal dimension, monitor unit, modulation index, fluence map complexity, weighted average of field area, weighted average of field perimeter, and small aperture ratio [Formula: see text]. The Spearman's rank correlation coefficient was calculated to analyze the correlation between these scores and gamma pass rate and plan quality variation. For planar QA, the most significant complexity index was fractal dimension for DMLC [Formula: see text] and weighted segment area for SMLC [Formula: see text] at low magnitude MLC error. For plan quality, the most significant complexity index was weighted segment perimeter for DMLC [Formula: see text] and weighted segment area for SMLC [Formula: see text] at low magnitude MLC error. The sensitivity of planar QA was weakly associated with the field complexity with low magnitude MLC error, but the plan quality robustness was associated with beam complexity. Plans with simple beams were more robust to MLC error. PACS number(s): 87.55
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spelling pubmed-56909282018-04-02 Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams Wang, Jiazhou Jin, Xiance Peng, Jiayuan Xie, Jiang Chen, Junchao Hu, Weigang J Appl Clin Med Phys Radiation Oncology Physics This study investigated the impact of beam complexities on planar quality assurance and plan quality robustness by introducing MLC errors in intensity‐modulate radiation therapy. Forty patients' planar quality assurance (QA) plans were enrolled in this study, including 20 dynamic MLC (DMLC) IMRT plans and 20 static MLC (SMLC) IMRT plans. The total beam numbers were 150 and 160 for DMLC and SMLC, respectively. Six different magnitudes of MLC errors were introduced to these beams. Gamma pass rates were calculated by comparing error‐free fluence and error‐induced fluence. The plan quality variation was acquired by comparing PTV coverage. Eight complexity scores were calculated based on the beam fluence and the MLC sequence. The complexity scores include fractal dimension, monitor unit, modulation index, fluence map complexity, weighted average of field area, weighted average of field perimeter, and small aperture ratio [Formula: see text]. The Spearman's rank correlation coefficient was calculated to analyze the correlation between these scores and gamma pass rate and plan quality variation. For planar QA, the most significant complexity index was fractal dimension for DMLC [Formula: see text] and weighted segment area for SMLC [Formula: see text] at low magnitude MLC error. For plan quality, the most significant complexity index was weighted segment perimeter for DMLC [Formula: see text] and weighted segment area for SMLC [Formula: see text] at low magnitude MLC error. The sensitivity of planar QA was weakly associated with the field complexity with low magnitude MLC error, but the plan quality robustness was associated with beam complexity. Plans with simple beams were more robust to MLC error. PACS number(s): 87.55 John Wiley and Sons Inc. 2016-05-08 /pmc/articles/PMC5690928/ /pubmed/27167272 http://dx.doi.org/10.1120/jacmp.v17i3.6022 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Wang, Jiazhou
Jin, Xiance
Peng, Jiayuan
Xie, Jiang
Chen, Junchao
Hu, Weigang
Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
title Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
title_full Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
title_fullStr Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
title_full_unstemmed Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
title_short Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
title_sort are simple imrt beams more robust against mlc error? exploring the impact of mlc errors on planar quality assurance and plan quality for different complexity beams
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690928/
https://www.ncbi.nlm.nih.gov/pubmed/27167272
http://dx.doi.org/10.1120/jacmp.v17i3.6022
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