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Clinical implementation of photon beam flatness measurements to verify beam quality

This work describes the replacement of Tissue Phantom Ratio (TPR) measurements with beam profile flatness measurements to determine photon beam quality during routine quality assurance (QA) measurements. To achieve this, a relationship was derived between the existing [Formula: see text] energy metr...

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Autores principales: Goodall, Simon, Harding, Nicholas, Simpson, Jake, Alexander, Louise, Morgan, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691013/
https://www.ncbi.nlm.nih.gov/pubmed/26699589
http://dx.doi.org/10.1120/jacmp.v16i6.5752
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author Goodall, Simon
Harding, Nicholas
Simpson, Jake
Alexander, Louise
Morgan, Steve
author_facet Goodall, Simon
Harding, Nicholas
Simpson, Jake
Alexander, Louise
Morgan, Steve
author_sort Goodall, Simon
collection PubMed
description This work describes the replacement of Tissue Phantom Ratio (TPR) measurements with beam profile flatness measurements to determine photon beam quality during routine quality assurance (QA) measurements. To achieve this, a relationship was derived between the existing [Formula: see text] energy metric and beam flatness, to provide baseline values and clinically relevant tolerances. The beam quality was varied around two nominal beam energy values for four matched Elekta linear accelerators (linacs) by varying the bending magnet currents and reoptimizing the beam. For each adjusted beam quality the [Formula: see text] was measured using an ionization chamber and Solid Water phantom. Two metrics of beam flatness were evaluated using two identical commercial ionization chamber arrays. A linear relationship was found between [Formula: see text] and both metrics of flatness, for both nominal energies and on all linacs. Baseline diagonal flatness ([Formula: see text]) values were measured to be 103.0% (ranging from 102.5% to 103.8%) for 6 MV and 102.7% (ranging from 102.6% to 102.8%) for 10 MV across all four linacs. Clinically acceptable tolerances of [Formula: see text] for 6 MV, and [Formula: see text] for 10 MV, were derived to equate to the current [Formula: see text] clinical tolerance of [Formula: see text]. Small variations in the baseline diagonal flatness values were observed between ionization chamber arrays; however, the rate of change of [Formula: see text] with diagonal flatness was found to remain within experimental uncertainty. Measurements of beam flatness were shown to display an increased sensitivity to variations in the beam quality when compared to TPR measurements. This effect is amplified for higher nominal energy photons. The derivation of clinical baselines and associated tolerances has allowed this method to be incorporated into routine QA, streamlining the process whilst also increasing versatility. In addition, the effect of beam adjustment can be observed in real time, allowing increased practicality during corrective and preventive maintenance interventions. PACS number: 87.56.Fc
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spelling pubmed-56910132018-04-02 Clinical implementation of photon beam flatness measurements to verify beam quality Goodall, Simon Harding, Nicholas Simpson, Jake Alexander, Louise Morgan, Steve J Appl Clin Med Phys Radiation Oncology Physics This work describes the replacement of Tissue Phantom Ratio (TPR) measurements with beam profile flatness measurements to determine photon beam quality during routine quality assurance (QA) measurements. To achieve this, a relationship was derived between the existing [Formula: see text] energy metric and beam flatness, to provide baseline values and clinically relevant tolerances. The beam quality was varied around two nominal beam energy values for four matched Elekta linear accelerators (linacs) by varying the bending magnet currents and reoptimizing the beam. For each adjusted beam quality the [Formula: see text] was measured using an ionization chamber and Solid Water phantom. Two metrics of beam flatness were evaluated using two identical commercial ionization chamber arrays. A linear relationship was found between [Formula: see text] and both metrics of flatness, for both nominal energies and on all linacs. Baseline diagonal flatness ([Formula: see text]) values were measured to be 103.0% (ranging from 102.5% to 103.8%) for 6 MV and 102.7% (ranging from 102.6% to 102.8%) for 10 MV across all four linacs. Clinically acceptable tolerances of [Formula: see text] for 6 MV, and [Formula: see text] for 10 MV, were derived to equate to the current [Formula: see text] clinical tolerance of [Formula: see text]. Small variations in the baseline diagonal flatness values were observed between ionization chamber arrays; however, the rate of change of [Formula: see text] with diagonal flatness was found to remain within experimental uncertainty. Measurements of beam flatness were shown to display an increased sensitivity to variations in the beam quality when compared to TPR measurements. This effect is amplified for higher nominal energy photons. The derivation of clinical baselines and associated tolerances has allowed this method to be incorporated into routine QA, streamlining the process whilst also increasing versatility. In addition, the effect of beam adjustment can be observed in real time, allowing increased practicality during corrective and preventive maintenance interventions. PACS number: 87.56.Fc John Wiley and Sons Inc. 2015-11-08 /pmc/articles/PMC5691013/ /pubmed/26699589 http://dx.doi.org/10.1120/jacmp.v16i6.5752 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Goodall, Simon
Harding, Nicholas
Simpson, Jake
Alexander, Louise
Morgan, Steve
Clinical implementation of photon beam flatness measurements to verify beam quality
title Clinical implementation of photon beam flatness measurements to verify beam quality
title_full Clinical implementation of photon beam flatness measurements to verify beam quality
title_fullStr Clinical implementation of photon beam flatness measurements to verify beam quality
title_full_unstemmed Clinical implementation of photon beam flatness measurements to verify beam quality
title_short Clinical implementation of photon beam flatness measurements to verify beam quality
title_sort clinical implementation of photon beam flatness measurements to verify beam quality
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691013/
https://www.ncbi.nlm.nih.gov/pubmed/26699589
http://dx.doi.org/10.1120/jacmp.v16i6.5752
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