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Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery

The small fields and sharp gradients typically encountered in proton radiosurgery require high spatial resolution dosimetric measurements, especially below 1–2 cm diameters. Radiochromic film provides high resolution, but requires postprocessing and special handling. Promising alternatives are diode...

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Autores principales: McAuley, Grant A., Teran, Anthony V., Slater, Jerry D., Slater, James M., Wroe, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691016/
https://www.ncbi.nlm.nih.gov/pubmed/26699554
http://dx.doi.org/10.1120/jacmp.v16i6.5391
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author McAuley, Grant A.
Teran, Anthony V.
Slater, Jerry D.
Slater, James M.
Wroe, Andrew J.
author_facet McAuley, Grant A.
Teran, Anthony V.
Slater, Jerry D.
Slater, James M.
Wroe, Andrew J.
author_sort McAuley, Grant A.
collection PubMed
description The small fields and sharp gradients typically encountered in proton radiosurgery require high spatial resolution dosimetric measurements, especially below 1–2 cm diameters. Radiochromic film provides high resolution, but requires postprocessing and special handling. Promising alternatives are diode detectors with small sensitive volumes (SV) that are capable of high resolution and real‐time dose acquisition. In this study we evaluated the PTW PR60020 proton dosimetry diode using radiation fields and beam energies relevant to radiosurgery applications. Energies of 127 and 157 MeV (9.7 to 15 cm range) and initial diameters of 8, 10, 12, and 20 mm were delivered using single‐stage scattering and four modulations (0, 15, 30, and 60 mm) to a water tank in our treatment room. Depth dose and beam profile data were compared with PTW Markus N23343 ionization chamber, EBT2 Gafchromic film, and Monte Carlo simulations. Transverse dose profiles were measured using the diode in "edge‐on" orientation or EBT2 film. Diode response was linear with respect to dose, uniform with dose rate, and showed an orientation‐dependent (i.e., beam parallel to, or perpendicular to, detector axis) response of less than 1%. Diode vs. Markus depth‐dose profiles, as well as Markus relative dose ratio vs. simulated dose‐weighted average lineal energy plots, suggest that any LET‐dependent diode response is negligible from particle entrance up to the very distal portion of the SOBP for the energies tested. Finally, while not possible with the ionization chamber due to partial volume effects, accurate diode depth‐dose measurements of 8, 10, and 12 mm diameter beams were obtained compared to Monte Carlo simulations. Because of the small SV that allows measurements without partial volume effects and the capability of submillimeter resolution (in edge‐on orientation) that is crucial for small fields and high‐dose gradients (e.g., penumbra, distal edge), as well as negligible LET dependence over nearly the full the SOBP, the PTW proton diode proved to be a useful high‐resolution, real‐time metrology device for small proton field radiation measurements such as would be encountered in radiosurgery applications. PACS numbers: 87.56.‐v, 87.56.jf, 87.56.Fc
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spelling pubmed-56910162018-04-02 Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery McAuley, Grant A. Teran, Anthony V. Slater, Jerry D. Slater, James M. Wroe, Andrew J. J Appl Clin Med Phys Radiation Oncology Physics The small fields and sharp gradients typically encountered in proton radiosurgery require high spatial resolution dosimetric measurements, especially below 1–2 cm diameters. Radiochromic film provides high resolution, but requires postprocessing and special handling. Promising alternatives are diode detectors with small sensitive volumes (SV) that are capable of high resolution and real‐time dose acquisition. In this study we evaluated the PTW PR60020 proton dosimetry diode using radiation fields and beam energies relevant to radiosurgery applications. Energies of 127 and 157 MeV (9.7 to 15 cm range) and initial diameters of 8, 10, 12, and 20 mm were delivered using single‐stage scattering and four modulations (0, 15, 30, and 60 mm) to a water tank in our treatment room. Depth dose and beam profile data were compared with PTW Markus N23343 ionization chamber, EBT2 Gafchromic film, and Monte Carlo simulations. Transverse dose profiles were measured using the diode in "edge‐on" orientation or EBT2 film. Diode response was linear with respect to dose, uniform with dose rate, and showed an orientation‐dependent (i.e., beam parallel to, or perpendicular to, detector axis) response of less than 1%. Diode vs. Markus depth‐dose profiles, as well as Markus relative dose ratio vs. simulated dose‐weighted average lineal energy plots, suggest that any LET‐dependent diode response is negligible from particle entrance up to the very distal portion of the SOBP for the energies tested. Finally, while not possible with the ionization chamber due to partial volume effects, accurate diode depth‐dose measurements of 8, 10, and 12 mm diameter beams were obtained compared to Monte Carlo simulations. Because of the small SV that allows measurements without partial volume effects and the capability of submillimeter resolution (in edge‐on orientation) that is crucial for small fields and high‐dose gradients (e.g., penumbra, distal edge), as well as negligible LET dependence over nearly the full the SOBP, the PTW proton diode proved to be a useful high‐resolution, real‐time metrology device for small proton field radiation measurements such as would be encountered in radiosurgery applications. PACS numbers: 87.56.‐v, 87.56.jf, 87.56.Fc John Wiley and Sons Inc. 2015-11-08 /pmc/articles/PMC5691016/ /pubmed/26699554 http://dx.doi.org/10.1120/jacmp.v16i6.5391 Text en © 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
McAuley, Grant A.
Teran, Anthony V.
Slater, Jerry D.
Slater, James M.
Wroe, Andrew J.
Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
title Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
title_full Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
title_fullStr Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
title_full_unstemmed Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
title_short Evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
title_sort evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691016/
https://www.ncbi.nlm.nih.gov/pubmed/26699554
http://dx.doi.org/10.1120/jacmp.v16i6.5391
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