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Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer

BRCAness has important implications in the management and treatment of patients with breast and ovarian cancer. In this study, we propose a computational framework to measure the BRCAness of breast and ovarian tumor samples based on their gene expression profiles. We define a characteristic profile...

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Detalles Bibliográficos
Autores principales:	Wang, Yue, Ung, Matthew H., Cantor, Sharon, Cheng, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691048/ https://www.ncbi.nlm.nih.gov/pubmed/29146938 http://dx.doi.org/10.1038/s41598-017-16138-2

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