Cargando…
Splenic glucocorticoid resistance following psychosocial stress requires physical injury
Mice exposed to chronic subordinate colony housing (CSC) stress show glucocorticoid (GC) resistance of in vitro lipopolysaccharide (LPS)-stimulated splenocytes, increased anxiety and colitis. Similar effects were reported in wounded mice exposed to social disruption (SDR). Here we show that CSC expo...
Autores principales: | Foertsch, Sandra, Füchsl, Andrea M., Faller, Sandra D., Hölzer, Hannah, Langgartner, Dominik, Messmann, Joanna, Strauß, Gudrun, Reber, Stefan O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691078/ https://www.ncbi.nlm.nih.gov/pubmed/29146967 http://dx.doi.org/10.1038/s41598-017-15897-2 |
Ejemplares similares
-
Abdominal surgery prior to chronic psychosocial stress promotes spleen cell (re)activity and glucocorticoid resistance
por: Foertsch, Sandra, et al.
Publicado: (2020) -
Mechanisms Underlying the Increased Plasma ACTH Levels in Chronic Psychosocially Stressed Male Mice
por: Füchsl, Andrea M., et al.
Publicado: (2013) -
Chronic Subordinate Colony Housing Paradigm: A Mouse Model to Characterize the Consequences of Insufficient Glucocorticoid Signaling
por: Langgartner, Dominik, et al.
Publicado: (2015) -
Changes in Functional Glucocorticoid Sensitivity of Isolated Splenocytes Induced by Chronic Psychosocial Stress – A Time Course Study
por: Kempter, Elena, et al.
Publicado: (2021) -
Chronic Psychosocial Stress and Negative Feedback Inhibition: Enhanced Hippocampal Glucocorticoid Signaling despite Lower Cytoplasmic GR Expression
por: Füchsl, Andrea M., et al.
Publicado: (2016)