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Redox Active Transition Metal ions Make Melanin Susceptible to Chemical Degradation Induced by Organic Peroxide

With aging, retinal pigment epithelium melanosomes, by fusion with the age pigment lipofuscin, form complex granules called melanolipofuscin. Lipofuscin granules may contain oxidized proteins and lipid hydroperoxides, which in melanolipofuscin could chemically modify melanin polymer, while transitio...

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Detalles Bibliográficos
Autores principales:	Zadlo, Andrzej, Pilat, Anna, Sarna, Michal, Pawlak, Anna, Sarna, Tadeusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691108/ https://www.ncbi.nlm.nih.gov/pubmed/28401421 http://dx.doi.org/10.1007/s12013-017-0793-6

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