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Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model

Accumulating evidence suggests a key role of the gut–microbiota–brain axis in the antidepressant actions of certain compounds. Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, showed rapid and sustained antidepressant effects in treatment-resistant depressed patients. In contrast, anot...

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Detalles Bibliográficos
Autores principales:	Qu, Youge, Yang, Chun, Ren, Qian, Ma, Min, Dong, Chao, Hashimoto, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691133/ https://www.ncbi.nlm.nih.gov/pubmed/29147024 http://dx.doi.org/10.1038/s41598-017-16060-7

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