Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5

Legionella pneumophila can cause Legionnaires’ disease and replicates intracellularly in a distinct Legionella-containing vacuole (LCV). LCV formation is a complex process that involves a plethora of type IV-secreted effector proteins. The effector RidL binds the Vps29 retromer subunit, blocks retro...

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Detalles Bibliográficos
Autores principales: Bärlocher, Kevin, Hutter, Cedric A. J., Swart, A. Leoni, Steiner, Bernhard, Welin, Amanda, Hohl, Michael, Letourneur, François, Seeger, Markus A., Hilbi, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691146/
https://www.ncbi.nlm.nih.gov/pubmed/29146912
http://dx.doi.org/10.1038/s41467-017-01512-5

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