Enforced GFI1 expression impedes human and murine leukemic cell growth

The differentiation of haematopoietic cells is regulated by a plethora of so-called transcription factors (TFs). Mutations in genes encoding TFs or graded reduction in their expression levels can induce the development of various malignant diseases such as acute myeloid leukaemia (AML). Growth Facto...

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Detalles Bibliográficos
Autores principales: Hönes, Judith M., Thivakaran, Aniththa, Botezatu, Lacramioara, Patnana, Pradeep, Castro, Symone Vitoriano da Conceição, Al-Matary, Yahya S., Schütte, Judith, Fischer, Karen B. I., Vassen, Lothar, Görgens, André, Dührsen, Ulrich, Giebel, Bernd, Khandanpour, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691148/
https://www.ncbi.nlm.nih.gov/pubmed/29147018
http://dx.doi.org/10.1038/s41598-017-15866-9

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