Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics

Individuals with 22q11.2 microdeletion syndrome (22q11.2 DS) show cognitive and behavioral dysfunctions, developmental delays in childhood and risk of developing schizophrenia and autism. Despite extensive previous studies in adult animal models, a possible embryonic root of this syndrome has not be...

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Detalles Bibliográficos
Autores principales: Amin, Hayder, Marinaro, Federica, De Pietri Tonelli, Davide, Berdondini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691208/
https://www.ncbi.nlm.nih.gov/pubmed/29146941
http://dx.doi.org/10.1038/s41598-017-15793-9

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