Specific Targeting of Melanotic Cells with Peptide Ligated Photosensitizers for Photodynamic Therapy

A strategy combining covalent conjugation of photosensitizers to a peptide ligand directed to the melanocortin 1 (MC1) receptor with the application of sequential LED light dosage at near-IR wavelengths was developed to achieve specific cytotoxicity to melanocytes and melanoma (MEL) with minimal col...

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Detalles Bibliográficos
Autores principales: Bigliardi, Paul Lorenz, Rout, Bhimsen, Pant, Aakanksha, Krishnan-Kutty, Viknish, Eberle, Alex N., Srinivas, Ramasamy, Burkett, Brendan Adrian, Bigliardi-Qi, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691209/
https://www.ncbi.nlm.nih.gov/pubmed/29146972
http://dx.doi.org/10.1038/s41598-017-15142-w

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