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DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways
Mitochondrial fission and selective mitochondrial autophagy (mitophagy) form an essential axis of mitochondrial quality control that plays a critical role in the development of cardiac ischemia-reperfusion (IR) injury. However, the precise upstream molecular mechanism of fission/mitophagy remains un...
Autores principales: | Jin, Qinhua, Li, Ruibing, Hu, Nan, Xin, Ting, Zhu, Pingjun, Hu, Shunying, Ma, Sai, Zhu, Hong, Ren, Jun, Zhou, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691221/ https://www.ncbi.nlm.nih.gov/pubmed/29149759 http://dx.doi.org/10.1016/j.redox.2017.11.004 |
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